Biotechnology and biopharmaceuticals : transforming proteins and genes into drugs /

• Κύριος συγγραφέας: Ho, Rodney J. Y.
• Άλλοι συγγραφείς: Gibaldi, Milo
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, New Jersey : Wiley Blackwell, [2013]
• Έκδοση: Second edition.
• Θέματα: Pharmaceutical biotechnology.; MEDICAL / Pharmacology; Biopharmaceutics.; Chemistry, Pharmaceutical.; Drug Design.; Drug design.; Electronic books.

Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs, Second Edition addresses the pivotal issues relating to translational science, including preclinical and clinical drug development, regulatory science, pharmaco-economics and cost-effectiveness considerations. The new...

Πίνακας περιεχομένων:

• Introduction to biopharmaceuticals
• Distinctions of biologic versus small molecule platforms in drug development
• Financing biologic drug development
• Application of biotechnology in drug discovery and early development
• Large-scale production of recombinant proteins
• Clinical pharmacology, toxicology, and therapeutic dosage & response
• Clinical evaluation and regulatory approval & enforcement of biopharmaceuticals
• Pharmacoeconomics and drug pricing / Garrison
• Antibodies and derivatives
• Hematopoietic growth and coagulation factors
• Cytokines and interferons
• Hormones
• Enzymes
• Vaccines / Hu, Ho
• Other biopharmaceutical products
• Advances in personalized medicine : pharmacogenetics in drug therapy
• Gene and cell therapy
• Pharmacoeconomics, outcome, and health technology assessment research in drug development
• Summary and future prospects.