MicroRNAs in medicine /
"MicroRNAs in Medicine provides an access point into the current literature on microRNA for both scientists and clinicians, with an up-to-date look at what is happening in the emerging field of microRNAs and their relevance to medicine. Each chapter is a comprehensive review, with descriptions...
| Μορφή: | Ηλ. βιβλίο |
|---|---|
| Γλώσσα: | English |
| Έκδοση: |
Hoboken, New Jersey :
Wiley-Blackwell,
[2013]
|
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- ""Title page
- Copyright page
- Foreword
- Preface
- Contributors
- 1: MicroRNAs: A Brief Introduction
- I. A Short History of Small RNAs
- II. Biogenesis of miRNAs
- III. miRNA Function: Controlling mRNA Stability, Degradation, and/or Translation
- IV. Regulating the Regulators: miRNA Control and Dysfunction in Disease
- V. Present and Future Perspectives for miRNAs in Medicine
- PART I: MicroRNAs as Physiological Regulators
- 2: MicroRNA Regulation of Stem Cell Fate and Reprogramming
- I. Introduction""
- ""II. MicroRNAs in Pluripotency and Establishment of Different Lineages
- III. MicroRNAs, Induced Pluripotency, and Transdifferentiation
- IV. Conclusion
- Acknowledgments
- 3: MicroRNAs as Regulators of Immunity
- I. Introduction
- II. Innate Immunity and miRNAs
- III. Adaptive Immunity and miRNAs
- IV. Conclusions and Future Directions
- 4: Regulation of Senescence by MicroRNAs
- I. Introduction: Senescence
- II. Posttranscriptional Regulation of Senescence by miRNAs
- III. Impact of SA-miRNAs on In Vivo Senescence""
- ""IV. Concluding Remarks and Future Perspectives
- Acknowledgments
- 5: The Emergence of GeroMIRs: A Group of MicroRNAs Implicated in Aging
- I. Introduction
- II. MiRNAs and Aging: Lessons from Invertebrates
- III. Changes in miRNA Expression during Mammalian Aging
- IV. MiRNA Modulation of Mammalian DNA Damage
- V. Micromanaging of Other Aging-Associated Pathways in Mammals
- VI. Conclusions and Future Perspectives
- 6: MicroRNAs and Hematopoiesis
- I. Introduction
- II. Lymphocyte Development
- III. Monocyte and Granulocyte Development""
- ""IV. Erythrocyte and Megakaryocyte Development
- V. Conclusions
- 7: MicroRNAs in Platelet Production and Activation
- I. Introduction
- II. miRNA Biogenesis and Function
- III. miRNAs and Megakaryocytopoiesis
- IV. Platelet miRNAs
- V. Platelet miRNAs as Biomarkers
- VI. Platelet Microparticles and miRNAs
- VII. Summary and Future Directions
- PART II: MicroRNAs in Infectious Disease: Hostâ€"Pathogen Interactions
- 8: MicroRNAs as Key Players in Host-Virus Interactions
- I. Introduction
- II. Host miRNAs and Virus Infection
- III. Viral miRNAs""
- ""IV. Biological Roles of Viral miRNAs
- V. Conclusions and Future Prospects
- Acknowledgments
- 9: MicroRNA Expression in Avian Herpesviruses
- I. Introduction
- II. Avian Herpesviruses and Associated Diseases
- III. Identification of miRNAs Encoded by Avian HerpesvirusES
- IV. Viral Orthologues of Host miRNAs
- V. Target Identification of Avian Herpesvirus miRNAs
- VI. Conclusions
- Acknowledgment
- 10: Function of Human Cytomegalovirus MicroRNAs and Potential Roles in Latency
- I. Introduction to Human Cytomegalovirus""
