Cancer and inflammation mechanisms : chemical, biological, and clinical aspects /

• Άλλοι συγγραφείς: Hiraku, Yūsuke (Επιμελητής έκδοσης), Kawanishi, Shōsuke, 1942- (Επιμελητής έκδοσης), Ōshima, Hiroshi, 1949- (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, New Jersey : Wiley, [2014]
• Θέματα: Carcinogenesis.; Inflammation > Mediators.; Inflammation > Immunological aspects.; Cancer > Immunological aspects.; Neoplasms > genetics.; HEALTH & FITNESS > Diseases > General.; MEDICAL > Clinical Medicine.; MEDICAL > Diseases.; MEDICAL > Evidence-Based Medicine.; MEDICAL > Internal Medicine.; Inflammation - Immunological aspects.; Electronic books.

Πίνακας περιεχομένων:

• Titlepage; Copyright; Contents; CONTRIBUTORS; PREFACE; CHAPTER 1 INFECTION, INFLAMMATION, AND CANCER: OVERVIEW; INFECTION, INFLAMMATION, AND CANCER: POSSIBLE MECHANISMS; PRODUCTION OF INFLAMMATORY MEDIATORS AND REACTIVE OXIDANTS; DNA AND PROTEIN DAMAGE BY ROSs AND RNSs; INFLAMMATION, EPIGENETIC MODIFICATION, AND microRNA; CONCLUDING REMARKS; REFERENCES; CHAPTER 2 STEM CELL THEORY AND INFLAMMATION-RELATED CANCER; CHRONIC INFLAMMATION AND CANCER; CANCER STEM CELLS; CARCINOGENIC FACTORS ARISING FROM CHRONIC INFLAMMATION; CHRONIC INFLAMMATION AND NORMAL STEM CELL FUNCTION
• Inflammation and the development and regulation of cancer stem cellsconcluding remarks; references; chapter 3 epithelial-mesenchymal transition: a link between cancer and inflammation; emt: a link between cancer and inflammation; q1: how are emt-permissive, inflammatory tumor microenvironments created?; q2: which emt-promoting signals are provided by inflammatory tumor microenvironments?; q3: how do emt-promoting signals influence the migratory behavior of tumor cells?; conclusions and future prospects; references; chapter 4 role of nitrative dna damage in inflammation- related carcinogenesis
• Dna damage during chronic inflammationliver fluke-induced cholangiocarcinoma; hpv-induced cervical cancer; ebv-induced nasopharyngeal carcinoma; dna damage induced by asbestos exposure; dna damage induced by carbon nanotube; soft tissue tumors and prognosis of tumor patients; conclusions and future prospects; references; chapter 5 lipid peroxidation-derived dna adducts and the role in inflammation-related carcinogenesis; lpo-derived reactive products contribute to dna damage; results and discussion; conclusions and future prospects; references
• CHAPTER 6 LEVEL OF INFLAMMATION-RELATED DNA ADDUCTS IN HUMAN TISSUESLEVEL OF 4-ONE- AND 4-OHE-DERIVED DNA ADDUCTS IN HUMAN TISSUES; BIOLOGICAL PROPERTIES OF 4-ONE- AND 4-OHE-DERIVED DNA ADDUCTS; INFLAMMATION AND FORMATION OF 4-ONE; CONCLUDING REMARKS; REFERENCES; CHAPTER 7 TOLL-LIKE RECEPTORS: ROLE IN INFLAMMATION AND CANCER; TLRs AND THEIR LIGANDS; TLR SIGNALING; MYD88-DEPENDENT SIGNALING PATHWAYS; TRIF-DEPENDENT SIGNALING PATHWAYS; INNATE IMMUNE CELLS IN CANCER TISSUES; TLRs AND TUMOR MICROENVIRONMENT; TOLL-LIKE RECEPTORS IN CANCER AND TUMOR THERAPY; ANTITUMOR ACTIVITY OF TLR LIGANDS
• ROLES OF TLRs IN CANCER PROGRESSIONCURRENT AND FUTURE DEVELOPMENTS; REFERENCES; CHAPTER 8 INFLAMMASOMES AND INFLAMMATION; NOD-LIKE RECEPTORS AND THE INFLAMMASOMES; THE NLRP3 INFLAMMASOME; THE IPAF INFLAMMASOME; THE NLRP1 INFLAMMASOME; THE NLRP12 INFLAMMASOME; THE NLRP7 INFLAMMASOME; THE NLRP6 INFLAMMASOME; THE AIM2 INFLAMMASOME; CYTOKINE TARGETS OF THE INFLAMMASOME; INFLAMMASOME DYSREGULATION IN DISEASE; CONCLUDING REMARKS; REFERENCES; CHAPTER 9 ACTIVATION-INDUCED CYTIDINE DEAMINASE: AN INTRINSIC GENOME MODULATOR IN INFLAMMATION-ASSOCIATED CANCER DEVELOPMENT