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05270nam a2200841 4500 |
| 001 |
ocn861789137 |
| 003 |
OCoLC |
| 005 |
20170124071850.3 |
| 006 |
m o d |
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131029s2014 njua ob 000 0 eng |
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|a 2013043100
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| 040 |
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|a DLC
|b eng
|e rda
|e pn
|c DLC
|d YDX
|d EBLCP
|d IDEBK
|d DG1
|d N$T
|d E7B
|d CUS
|d CDX
|d OCLCF
|d VRC
|d YDXCP
|d RECBK
|d NLGGC
|d OCLCQ
|d OCLCO
|d COO
|d DEBSZ
|d DEBBG
|d GrThAP
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| 019 |
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|a 905856765
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|a 9781118836323
|q (pdf)
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|a 1118836324
|q (pdf)
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|a 9781118836309
|q (epub)
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|a 1118836308
|q (epub)
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|a 9781118836538
|q (mobi)
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|a 1118836537
|q (mobi)
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|a 9781118836507
|q (electronic bk.)
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|a 1118836502
|q (electronic bk.)
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| 020 |
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|z 9780470566688
|q (cloth)
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|a 047056668X
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|a 9780470566688
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1 |
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|a DEBBG
|b BV043396304
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| 035 |
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|a (OCoLC)861789137
|z (OCoLC)905856765
|
| 042 |
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|a pcc
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| 050 |
0 |
0 |
|a QP370
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| 060 |
1 |
0 |
|a QU 136
|
| 072 |
|
7 |
|a MED
|x 075000
|2 bisacsh
|
| 072 |
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7 |
|a SCI
|x 036000
|2 bisacsh
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| 082 |
0 |
0 |
|a 612.8/2
|2 23
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| 049 |
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|a MAIN
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| 245 |
0 |
0 |
|a Cyclic-nucleotide phosphodiesterases in the central nervous system :
|b from biology to drug discovery /
|c edited by Nicholas J. Brandon, Anthony R. West.
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| 264 |
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1 |
|a Hoboken, New Jersey :
|b John Wiley & Sons, Inc.,
|c [2014]
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| 300 |
|
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|a 1 online resource (xi, 386 pages) :
|b illustrations (some color).
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| 336 |
|
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|a text
|b txt
|2 rdacontent
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| 337 |
|
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Wiley series in drug discovery and development
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| 504 |
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|a Includes bibliographical references.
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| 505 |
0 |
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|a Phosphodiesterases and cyclic nucleotide signaling in the CNS / Marco Conti and Wito Richter -- Putting together the pieces of phosphodiesterase distribution patterns in the brain : a jigsaw puzzle of cyclic nucleotide regulation / Michy P. Kelly -- Compartmentalization and regulation of cyclic nucleotide signalling in the CNS / Manuela Zaccolo and Alessandra Stangherlin -- Pharmacological manipulation of cyclic nucleotide phosphodiesterase signaling for the treatment of neurological and psychiatric disorders in the brain / Frank S. Menniti, Niels Plath, Christopher J. Schmidt, and Niels Svenstrup -- Recent results in phosphodiesterase inhibitor development and CNS applications / David P. Rotella -- Crystal structures of phosphodiesterases and implication on discovery of inhibitors / Hengming Ke, Huanchen Wang, Mengchun Ye, and Yingchun Huang -- Inhibition of cyclic nucleotide phosphodiesterases to regulate memory / Han-Ting Zhang, Ying Xu, James O'Donnell -- Emerging role for PDE4 in neuropsychiatric disorders : translating advances from genetic studies into relevant therapeutic strategies / Sandra P. Zoubovsky, Nicholas J. Brandon P, and Akira Sawa -- Beyond erectile dysfunction : understanding PDE5 activity in the central nervous system / Eva P.P. Bollen, Kris Rutten, Olga A.H. Reneerkens, Harry M.W Steinbusch, and Jos Prickaerts -- Molecular and cellular understanding of PDE10A : a dual-substrate phosphodiesterase with therapeutic potential to modulate basal ganglia function / Erik I. Charych and Nicholas J. Brandon -- Role of cyclic nucleotide signaling and phosphodiesterase activation in the modulation of electrophysiological activity of central neurons / Sarah Threlfell and Anthony R. West -- The role of phosphodiesterases in dopamine systems governing motivated behavior / Gretchen L. Snyder, Akinori Nishi, and Joseph P. Hendrick -- Inhibition of phosphodiesterases as a strategy for treatment of spinal cord injury / Elena Nikulina and Marie T. Filbin.
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| 588 |
0 |
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|a Print version record and CIP data provided by publisher.
|
| 650 |
|
0 |
|a Cyclic nucleotide phosphodiesterases.
|
| 650 |
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0 |
|a Central nervous system
|x Physiology.
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| 650 |
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0 |
|a Nucleotides, Cyclic.
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| 650 |
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2 |
|a 3',5'-Cyclic-AMP Phosphodiesterases
|x metabolism.
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| 650 |
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2 |
|a 3',5'-Cyclic-AMP Phosphodiesterases
|x therapeutic use.
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| 650 |
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2 |
|a Central Nervous System
|x physiology.
|
| 650 |
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2 |
|a Central Nervous System Diseases
|x drug therapy.
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| 650 |
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2 |
|a Drug Discovery.
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| 650 |
|
7 |
|a MEDICAL
|x Physiology.
|2 bisacsh
|
| 650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Human Anatomy & Physiology.
|2 bisacsh
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| 650 |
|
7 |
|a Central nervous system.
|2 fast
|0 (OCoLC)fst00850724
|
| 650 |
|
7 |
|a Cyclic nucleotide phosphodiesterases.
|2 fast
|0 (OCoLC)fst00885846
|
| 655 |
|
4 |
|a Electronic books.
|
| 655 |
|
0 |
|a Electronic books.
|
| 700 |
1 |
|
|a Brandon, Nicholas J.,
|e editor.
|
| 700 |
1 |
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|a West, Anthony R.,
|d 1970-
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Cyclic-nucleotide phosphodiesterases in the central nervous system.
|d Hoboken, New Jersey : John Wiley & Sons, Inc., [2014]
|z 9780470566688
|w (DLC) 2013042742
|w (OCoLC)861755359
|
| 830 |
|
0 |
|a Wiley series in drug discovery and development.
|
| 856 |
4 |
0 |
|u https://doi.org/10.1002/9781118836507
|z Full Text via HEAL-Link
|
| 994 |
|
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|a 92
|b DG1
|
