Cyclic-nucleotide phosphodiesterases in the central nervous system : from biology to drug discovery /

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Brandon, Nicholas J. (Επιμελητής έκδοσης), West, Anthony R., 1970- (Επιμελητής έκδοσης)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Hoboken, New Jersey : John Wiley & Sons, Inc., [2014]
Σειρά:Wiley series in drug discovery and development.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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049 |a MAIN 
245 0 0 |a Cyclic-nucleotide phosphodiesterases in the central nervous system :  |b from biology to drug discovery /  |c edited by Nicholas J. Brandon, Anthony R. West. 
264 1 |a Hoboken, New Jersey :  |b John Wiley & Sons, Inc.,  |c [2014] 
300 |a 1 online resource (xi, 386 pages) :  |b illustrations (some color). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Wiley series in drug discovery and development 
504 |a Includes bibliographical references. 
505 0 |a Phosphodiesterases and cyclic nucleotide signaling in the CNS / Marco Conti and Wito Richter -- Putting together the pieces of phosphodiesterase distribution patterns in the brain : a jigsaw puzzle of cyclic nucleotide regulation / Michy P. Kelly -- Compartmentalization and regulation of cyclic nucleotide signalling in the CNS / Manuela Zaccolo and Alessandra Stangherlin -- Pharmacological manipulation of cyclic nucleotide phosphodiesterase signaling for the treatment of neurological and psychiatric disorders in the brain / Frank S. Menniti, Niels Plath, Christopher J. Schmidt, and Niels Svenstrup -- Recent results in phosphodiesterase inhibitor development and CNS applications / David P. Rotella -- Crystal structures of phosphodiesterases and implication on discovery of inhibitors / Hengming Ke, Huanchen Wang, Mengchun Ye, and Yingchun Huang -- Inhibition of cyclic nucleotide phosphodiesterases to regulate memory / Han-Ting Zhang, Ying Xu, James O'Donnell -- Emerging role for PDE4 in neuropsychiatric disorders : translating advances from genetic studies into relevant therapeutic strategies / Sandra P. Zoubovsky, Nicholas J. Brandon P, and Akira Sawa -- Beyond erectile dysfunction : understanding PDE5 activity in the central nervous system / Eva P.P. Bollen, Kris Rutten, Olga A.H. Reneerkens, Harry M.W Steinbusch, and Jos Prickaerts -- Molecular and cellular understanding of PDE10A : a dual-substrate phosphodiesterase with therapeutic potential to modulate basal ganglia function / Erik I. Charych and Nicholas J. Brandon -- Role of cyclic nucleotide signaling and phosphodiesterase activation in the modulation of electrophysiological activity of central neurons / Sarah Threlfell and Anthony R. West -- The role of phosphodiesterases in dopamine systems governing motivated behavior / Gretchen L. Snyder, Akinori Nishi, and Joseph P. Hendrick -- Inhibition of phosphodiesterases as a strategy for treatment of spinal cord injury / Elena Nikulina and Marie T. Filbin. 
588 0 |a Print version record and CIP data provided by publisher. 
650 0 |a Cyclic nucleotide phosphodiesterases. 
650 0 |a Central nervous system  |x Physiology. 
650 0 |a Nucleotides, Cyclic. 
650 2 |a 3',5'-Cyclic-AMP Phosphodiesterases  |x metabolism. 
650 2 |a 3',5'-Cyclic-AMP Phosphodiesterases  |x therapeutic use. 
650 2 |a Central Nervous System  |x physiology. 
650 2 |a Central Nervous System Diseases  |x drug therapy. 
650 2 |a Drug Discovery. 
650 7 |a MEDICAL  |x Physiology.  |2 bisacsh 
650 7 |a SCIENCE  |x Life Sciences  |x Human Anatomy & Physiology.  |2 bisacsh 
650 7 |a Central nervous system.  |2 fast  |0 (OCoLC)fst00850724 
650 7 |a Cyclic nucleotide phosphodiesterases.  |2 fast  |0 (OCoLC)fst00885846 
655 4 |a Electronic books. 
655 0 |a Electronic books. 
700 1 |a Brandon, Nicholas J.,  |e editor. 
700 1 |a West, Anthony R.,  |d 1970-  |e editor. 
776 0 8 |i Print version:  |t Cyclic-nucleotide phosphodiesterases in the central nervous system.  |d Hoboken, New Jersey : John Wiley & Sons, Inc., [2014]  |z 9780470566688  |w (DLC) 2013042742  |w (OCoLC)861755359 
830 0 |a Wiley series in drug discovery and development. 
856 4 0 |u https://doi.org/10.1002/9781118836507  |z Full Text via HEAL-Link 
994 |a 92  |b DG1