How to design, analyse and report cluster randomised trials in medicine and health related research /

How to design, analyse and report cluster randomised trials in medicine and health related research /

"A much-needed guide to the design and analysis of cluster randomized trials, How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research delivers practical guidance on the design and analysis of cluster randomised trials (cRCTs) in healthcare research. D...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Campbell, Michael J., 1950- (Συγγραφέας), Walters, Stephen John (Συγγραφέας)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Chichester, West Sussex : John Wiley & Sons, 2014.
Σειρά:Statistics in practice.
Θέματα:
Clinical trials.
Medicine > Research > Statistical methods.
Medical care > Research > Methods.
Randomized Controlled Trials as Topic.
HEALTH & FITNESS > Holism.
HEALTH & FITNESS > Reference.
MEDICAL > Alternative Medicine.
MEDICAL > Atlases.
MEDICAL > Essays.
MEDICAL > Family & General Practice.
MEDICAL > Holistic Medicine.
MEDICAL > Osteopathy.
Data Interpretation, Statistical.
Health Services Research > methods.
Research Design.
Electronic books.
Διαθέσιμο Online:Full Text via HEAL-Link
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049 |a MAIN 
100 1 |a Campbell, Michael J.,  |d 1950-  |e author. 
245 1 0 |a How to design, analyse and report cluster randomised trials in medicine and health related research /  |c Michael J. Campbell and Stephen J. Walters. 
264 1 |a Chichester, West Sussex :  |b John Wiley & Sons,  |c 2014. 
300 |a 1 online resource. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Statistics in practice 
504 |a Includes bibliographical references and index. 
520 |a "A much-needed guide to the design and analysis of cluster randomized trials, How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research delivers practical guidance on the design and analysis of cluster randomised trials (cRCTs) in healthcare research. Detailing how to use Stata and SPSS and R for statistical analysis, each analysis technique is carefully explained with mathematics kept to a minimum. Written in a clear, accessible style by experienced statisticians, the text provides a practical approach for applied statisticians and biomedical researchers"--Provided by publisher. 
588 0 |a Print version record and CIP data provided by publisher. 
505 0 |a Statistics in Practice; Title Page; Copyright; Preface; Acronyms and abbreviations; Chapter 1: Introduction; 1.1 Randomised controlled trials; 1.2 Complex interventions; 1.3 History of cluster randomised trials; 1.4 Cohort and field trials; 1.5 The field/community trial; 1.6 The cohort trial; 1.7 Field versus cohort designs; 1.8 Reasons for cluster trials; 1.9 Between- and within-cluster variation; 1.10 Random-effects models for continuous outcomes; 1.11 Random-effects models for binary outcomes; 1.12 The design effect; 1.13 Commonly asked questions; 1.14 Websources; Chapter 2: Design issues. 
505 8 |a 2.1 Introduction2.2 Issues for a simple intervention; 2.3 Complex interventions; 2.4 Recruitment bias; 2.5 Matched-pair trials; 2.6 Other types of designs; 2.7 Other design issues; 2.8 Strategies for improving precision; 2.9 Randomisation; Exercise; Appendix 2.A; Chapter 3: Sample size: How many subjects/clusters do I need for my cluster randomised controlled trial?; 3.1 Introduction; 3.2 Sample size for continuous data -- comparing two means; 3.3 Sample size for binary data -- comparing two proportions; 3.4 Sample size for ordered categorical (ordinal) data; 3.5 Sample size for rates. 
505 8 |a 3.6 Sample size for survival3.7 Equivalence/non-inferiority studies; 3.8 Unknown standard deviation and effect size; 3.9 Practical problems; 3.10 Number of clusters fixed; 3.11 Values of the ICC; 3.12 Allowing for imprecision in the ICC; 3.13 Allowing for varying cluster sizes; 3.14 Sample size re-estimation; 3.15 Matched-pair studies; 3.16 Multiple outcomes/endpoints; 3.17 Three or more groups; 3.18 Crossover trials; 3.19 Post hoc sample size calculations; 3.20 Conclusion: Usefulness of sample size calculations; 3.21 Commonly asked questions; Exercise; Appendix 3.A. 
505 8 |a Chapter 4: Simple analysis of cRCT outcomes using aggregate cluster-level summaries4.1 Introduction; 4.2 Aggregate cluster-level analysis-carried out at the cluster level, using aggregate summary data; 4.3 Statistical methods for continuous outcomes; 4.4 Mann-Whitney U test; 4.5 Statistical methods for binary outcomes; 4.6 Analysis of a matched design; 4.7 Discussion; 4.8 Commonly asked question; Exercise; Chapter 5: Regression methods of analysis for continuous outcomes using individual person-level data; 5.1 Introduction; 5.2 Incorrect models. 
505 8 |a 5.3 Linear regression with robust standard errors5.4 Random-effects general linear models in a cohort study; 5.5 Marginal general linear model with coefficients estimated by generalised estimating equations (GEE); 5.6 Summary of methods; 5.7 Adjusting for individual-level covariates in cohort studies; 5.8 Adjusting for cluster-level covariates in cohort studies; 5.9 Models for cross-sectional designs; 5.10 Discussion of model fitting; Exercise; Appendix 5.A; Chapter 6: Regression methods of analysis for binary, count and time-to-event outcomes for a cluster randomised controlled trial. 
650 0 |a Clinical trials. 
650 0 |a Medicine  |x Research  |x Statistical methods. 
650 0 |a Medical care  |x Research  |x Methods. 
650 4 |a Randomized Controlled Trials as Topic. 
650 7 |a HEALTH & FITNESS  |x Holism.  |2 bisacsh 
650 7 |a HEALTH & FITNESS  |x Reference.  |2 bisacsh 
650 7 |a MEDICAL  |x Alternative Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Atlases.  |2 bisacsh 
650 7 |a MEDICAL  |x Essays.  |2 bisacsh 
650 7 |a MEDICAL  |x Family & General Practice.  |2 bisacsh 
650 7 |a MEDICAL  |x Holistic Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Osteopathy.  |2 bisacsh 
650 2 |a Randomized Controlled Trials as Topic. 
650 2 |a Data Interpretation, Statistical. 
650 2 |a Health Services Research  |x methods. 
650 2 |a Research Design. 
655 4 |a Electronic books. 
700 1 |a Walters, Stephen John,  |e author. 
776 0 8 |i Print version:  |a Campbell, Michael J., 1950- author.  |t How to design, analyse and report cluster randomised trials in medicine and health related research.  |d Chichester, West Sussex : John Wiley & Sons, 2014  |z 9781119992028  |w (DLC) 2013048574 
830 0 |a Statistics in practice. 
856 4 0 |u https://doi.org/10.1002/9781118763452  |z Full Text via HEAL-Link 
994 |a 92  |b DG1 

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