Ligand design in medicinal inorganic chemistry /

• Άλλοι συγγραφείς: Storr, Tim (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Chichester, West Sussex : John Wiley & Sons Inc., 2014.
• Θέματα: DNA-drug interactions.; Ligand binding (Biochemistry); Drugs > Design.; Pharmaceutical chemistry.; ADN.; Medicaments > Disseny.; Lligands (Bioquímica); Química farmacèutica.; MEDICAL > Physiology.; SCIENCE > Life Sciences > Human Anatomy & Physiology.; Llibres electrònics.; Electronic books.

Πίνακας περιεχομένων:

• Introduction to ligand design in medicinal inorganic chemistry
• Platinum-based anticancer agents
• Coordination chemistry and ligand design in the development of metal based radiopharmaceuticals
• Ligand design in D-block optical imaging agents and sensors
• Luminescent lanthanoid probes
• Metal complexes of carbohydrate-targeted ligands in medicinal inorganic chemistry
• Design of Schiff base-derived ligands: applications in therapeutics and medical diagnosis
• Metal-based antimalarial agents
• Therapeutic gold compounds
• Ligand design to target and modulate metal-protein interactions in neurodegenerative diseases
• Rational design of copper and iron chelators to treat Wilson's disease and hemochromatosis
• MRI contrast agents
• Photoactivatable metal complexes and their use in biology and medicine
• Metalloprotein inhibitors
• Ruthenium anticancer compounds with biologically-derived ligands.