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05274nam a2200553 4500 |
| 001 |
ocn874147039 |
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OCoLC |
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20180501122015.0 |
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m o d |
| 007 |
cr cn||||||||| |
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140123t20142014cauaf ob 001 0 eng d |
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|a E7B
|b eng
|e rda
|e pn
|c E7B
|d OCLCO
|d EBLCP
|d OPELS
|d N$T
|d OCLCF
|d CDX
|d DEBSZ
|d OCLCO
|d OCLCQ
|d OCLCO
|d OCL
|d OCLCO
|d OCLCQ
|d GrThAP
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| 019 |
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|a 867928819
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|a 9780128003572
|q (e-book)
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|a 012800357X
|q (e-book)
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|a 0128000988
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| 020 |
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|a 9780128000984
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| 035 |
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|a (OCoLC)874147039
|z (OCoLC)867928819
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| 050 |
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4 |
|a QR355
|b .A383 2014eb
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| 072 |
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7 |
|a SCI
|x 027000
|2 bisacsh
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| 082 |
0 |
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|a 576
|2 23
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| 049 |
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|a TEFA
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| 245 |
0 |
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|a Advances in virus research.
|n Volume 88 /
|c edited by Karl Maramorosch, Frederick A. Murphy.
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| 250 |
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|a First edition.
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| 264 |
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1 |
|a San Diego, California :
|b Academic Press,
|c 2014.
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| 264 |
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4 |
|c ©2014
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| 300 |
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|a 1 online resource (403 pages, [11] pages of plates) :
|b color illustrations, tables
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 504 |
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|a Includes bibliographical references at the end of each chapters and index.
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| 588 |
0 |
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|a Online resource; title from PDF title page (ebrary, viewed January 23, 2014).
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| 505 |
0 |
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|a Front Cover; Advances in Virus Research; Copyright; Contents; Contributors; Chapter One: Revisiting Dengue Virus-Host Cell Interaction: New Insights into Molecular and Cellular Virology; 1. Introduction; 2. Dengue Disease; 2.1. History and epidemiology; 2.2. Transmission and course of infection; 2.3. Pathogenesis; 3. The Molecular Biology of DENV; 3.1. An overview of the DENV replication cycle; 3.2. The Dengue virus particle: Biogenesis, release, and entry properties; 3.3. Structural and functional elements of DENV genome; 3.4. Viral proteins and their function; 3.5. Viral RNA replication.
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| 505 |
8 |
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|a 4. The DENV-Host Cell Interface: High-Throughput Approaches to Identify Relevant Host Cell Factors and Pathways4.1. Identification of host cell factors of relevance for the DENV replication cycle by using RNAi screens; 4.2. Protein interaction networks; 4.3. Transcriptome, proteome, and lipidome analyses; 4.4. Chemical compounds screens; 5. Host Dependency Factors and Their Role in the DENV Replication Cycle; 5.1. Virus attachment and host cell receptors; 5.2. Mechanism of virus entry and involved host cell pathways; 5.3. RNA translation and replication.
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| 505 |
8 |
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|a 5.3.1. Role of autophagy in DENV replication5.3.2. Lipid metabolism and its role in DENV replication; 5.3.3. Role of unfolded protein response and ubiquitin-proteasome system in DENV replication; 5.3.4. RNA-binding host cell factors involved in DENV replication; 5.3.5. Replicase-interacting host cell factors involved in DENV replication; 5.4. Assembly and release; 6. Host Restriction Factors and Their Role in the DENV Replication Cycle; 6.1. PRRs and host cell pathways involved in recognition of DENV infection; 6.2. Inhibition of the IFN system by DENV.
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| 505 |
8 |
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|a 6.3. IFN-stimulated genes suppressing DENV replication6.4. Non-IFN pathways involved in suppression of virus replication and hijacked by DENV; 7. Host Cell Factors as Target for Antiviral Agents; 8. Concluding Remarks; Acknowledgments; References; Chapter Two: KSHV: Pathways to Tumorigenesis and Persistent Infection; 1. Malignancies and Syndromes Linked with KSHV Infection; 1.1. Kaposi ́s sarcoma; 1.2. Primary effusion lymphoma; 1.3. Multicentric Castleman ́s disease; 1.4. KSHV-associated inflammatory cytokine syndrome; 1.5. KSHV immune reconstitution inflammatory syndrome.
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| 505 |
8 |
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|a 2. KSHV Biology: Virion, Transmission, and Viral Lifecycle2.1. Viral latency and associated proteins; 2.1.1. LANA; 2.1.2. vCyclin; 2.1.3. vFLIP; 2.1.4. The kaposins; 2.1.5. KSHV microRNAs; 2.2. KSHV lytic cycle; 3. Lytic KSHV Proteins Involved in Cell Growth and Survival; 3.1. K1; 3.2. Viral G-protein-coupled receptor; 3.3. Viral interleukin-6; 3.4. K15; 4. KSHV ́s Activation and Evasion of the Host Immune Response; 4.1. Immune activation; 4.2. Evasion of the adaptive immune response; 4.3. Evasion of the innate immune response; 4.3.1. Interferon and IRF inhibition by KSHV.
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| 520 |
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|a The first review series in virology and published since 1953, Advances in Virus Research covers a diverse range of in-depth reviews, providing a valuable overview of the field. Contributions from leading authoritiesComprehensive reviews for general and specialist useFirst and longest-running review series in virology.
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| 650 |
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0 |
|a Virology
|v Periodicals.
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| 650 |
|
0 |
|a Virology
|x Research.
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| 650 |
|
7 |
|a SCIENCE
|x Life Sciences
|x Evolution.
|2 bisacsh
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| 650 |
|
7 |
|a Virology.
|2 fast
|0 (OCoLC)fst01167670
|
| 650 |
|
7 |
|a Virology
|x Research.
|2 fast
|0 (OCoLC)fst01167675
|
| 655 |
|
4 |
|a Electronic books.
|
| 655 |
|
7 |
|a Periodicals
|2 fast
|0 (OCoLC)fst01411641
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| 700 |
1 |
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|a Maramorosch, Karl,
|e editor.
|
| 700 |
1 |
|
|a Murphy, Frederick A.
|
| 776 |
0 |
8 |
|i Print version:
|t Advances in virus research.
|b First edition.
|d San Diego, California : Academic Press, ©2014
|h x, 380 pages
|z 9780128000984
|
| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/00653527/88
|z Full Text via HEAL-Link
|
