Statistical thinking for non-statisticians in drug regulation /

Statistical Thinking for Non-Statisticians in Drug Regulation, Second Edition, is a need-to-know guide to understanding statistical methodology, statistical data and results within drug development and clinical trials.It provides non-statisticians working in the pharmaceutical and medical device ind...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Kay, R. (Richard), 1949- (Συγγραφέας)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Chichester, West Sussex, UK ; Hoboken, New Jersey : Wiley Blackwell, 2015.
Έκδοση:Second edition.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Basic ideas in clinical trial design
  • Sampling and inferential statistics
  • Confidence intervals and p-values
  • Tests for simple treatment comparisons
  • Adjusting the analysis
  • Regression and analysis of covariance
  • Intention-to-treat and analysis sets
  • Power and sample size
  • Statistical significance and clinical importance
  • Multiple testing
  • Non-parametric and related methods
  • Equivalence and non-inferiority
  • The analysis of survival data
  • Interim analysis and data monitoring committees
  • Bayesian statistics
  • Adaptive designs
  • Observational studies
  • Meta-analysis
  • Methods for the safety analysis and safety monitoring
  • Diagnosis
  • The role of statistics and statisticians.