An introduction to high content screening : imaging technology, assay development, and data analysis in biology and drug discovery /

• Other Authors: Haney, Steven A. (Editor), Bowman, Doug, active 2014 (Editor), Chakravarty, Arijit (Editor), Davies, Anthony, active 2014 (Editor), Shamu, Caroline (Editor)
• Format: eBook
• Language: English
• Published: Hoboken, New Jersey : John Wiley & Sons Inc., [2015]
• Subjects: Drugs > Analysis.; Drug development.; Drug Design.; Systems Biology > methods.; Data Interpretation, Statistical.; Drug Evaluation, Preclinical > methods.; Image Processing, Computer-Assisted > methods.; Models, Biological.; MEDICAL > Pharmacology.; Electronic books.

Table of Contents:

• Introduction / Steven Haney
• Fluorescence and cell labeling / Anthony Davies, Steven Haney
• Microscopy fundamentals / Steven Haney, Anthony Davies, Doug Bowman
• Image processing / John Bradley, Doug Bowman, Arijit Chakravarty
• Selecting and setting up a high content imaging platform / Craig Furman, Doug Bowman, Anthony Davies, Caroline Shamu, Steven Haney
• Informatics considerations / Jay Copeland, Caroline Shamu
• Basic high content assay development / Steven Haney, Doug Bowman
• Designing metrics for high content assays / Arijit Chakravarty, Steven Haney, Doug Bowman
• Analyzing well-level data / Steven Haney, Arijit Chakravarty
• Analyzing cell level data / Steven Haney, Lin Guey, Arijit Chakravarty
• Designing robust assays / Arijit Chakrivarty, Doug Bowman, Anthony Davies, Caroline Shamu
• Automation and screening / John Donovan, Arijit Chakravarty, Anthony Davies, Steven Haney, Doug Bowman, John Ringling, Ben Knight
• High content analysis for tissue samples / Kristine Burke, Vaishali Sinde, Alice McDonald, Doug Bowman, Arijit Chakrivarty
• Factoring and clustering high content data / Steven Haney, Arijit Chakravarty
• Supervised machine learning / Jeff Palmer, Arijit Chakravarty.