Drug metabolism prediction /

• Other Authors: Kirchmair, Johannes (Editor)
• Format: eBook
• Language: English
• Published: Weinheim, Germany : Wiley-VCH, 2014.
• Series: Methods and principles in medicinal chemistry.
• Subjects: Drugs > Metabolism.; Enzymes > Effect of drugs on.; MEDICAL > Pharmacology.; Electronic books.

The first professional reference on this highly relevant topic, for drug developers, pharmacologists and toxicologists. The authors provide more than a systematic overview of computational tools and knowledge bases for drug metabolism research and their underlying principles. They aim to convey thei...

Table of Contents:

• Part 1. Introduction
• Part 2. Software, web servers and data resources to study metabolism
• Part 3. Computational approaches to study cytochrome P450 enzymes
• Part 4. Computational approaches to study sites and products of metabolism
• Part 5. Computational approaches to study enzymes inhibition and induction
• Part 6. Experimental approaches to study metabolism.