Regulated cell death.

Regulated cell death. Volume 545, Part B, Necroptotic, autophagic and other non-apoptotic mechanisms /

This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches.

Bibliographic Details
Other Authors: Ashkenazi, Avi, Wells, James A. (James Allen), 1950-, Yuan, Junying
Format: eBook
Language:English
Published: San Diego, CA : Academic Press, 2014.
Ã2014
Series:Methods in enzymology ; volume 545.
Subjects:
Cell death.
Autophagic vacuoles.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Cell Death.
Autophagy.
Electronic books.
Online Access:Full Text via HEAL-Link
Table of Contents:
  • Assays for necroptosis and activity of RIP kinases
  • IAP family of cell death and signaling regulators
  • Activation of the NLRP3 inflammasome by proteins that signal for necroptosis
  • Characterization of the ripoptosome and its components: implications for anti-inflammatory and cancer therapy
  • Tools and techniques to study ligand-receptor interactions and receptor activation by TNF superfamily members
  • Necrotic cell death in Caenorhabditis elegans
  • Noncanonical cell death in the nematode Caenorhabditis elegans
  • Autophagy and cell death in the fly
  • Structural studies of death receptors
  • Use of E2~ubiquitin conjugates for the characterization of ubitquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins
  • Muiltidimensional profiling in the invetigation of small-molecule-induced cell death.

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