Cirrhosis : a practical guide to management /

Cirrhosis: a practical guide to management providesgastroenterologists and hepatologists with an up-to-date clinicalguide presenting the very best evidence-based practice in thediagnosis, treatment and management of liver cirrhosis and its manycomplications. Designed to offer practical guidance at a...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Lee, Samuel S., 1954- (Επιμελητής έκδοσης), Moreau, Richard, 1951- (Επιμελητής έκδοσης)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Chichester, West Sussex ; Hoboken, NJ : Wiley-Blackwell, 2015.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Cirrhosis: A Practical Guide to Management; Contents; List of contributors; Foreword; List of abbreviations; Part 1: Diagnosis and pathophysiology; 1. Clinical clues to the diagnosis of cirrhosis; Introduction; Clinical presentation; Patient history; Abdominal distension (ascites); Jaundice; Upper gastrointestinal bleeding; Hepatic encephalopathy; Etiologic history taking; Alcohol intake: how much is significant; History of other risk factors; Examination; General examination; Nutritional status; Cutaneous clues; Spider angioma; Palmar erythema; Dupuytren's contracture; Leukonychia.
  • Muehrcke's nailsBier spots; Paper-money skin; Hypogonadism and gynecomastia; Parotidomegaly; Other manifestations; Abdominal examination; Abdominal veins; Cruveilhier-Baumgarten murmur; Examination of the liver; Examination of the spleen; Examination for ascites; Neurologic examination; References; 2. Diagnostic laboratory tests; Introduction; Tests that detects hepatic injury (Table 2.1); Serum aminotransferases; Serum biliary enzymes; Tests of hepatic metabolism (Table 2.1); Serum bilirubin; Serum ammonia; Indocyanine green and bromsulphalein tests.
  • Tests of hepatic biosynthetic function (Table 2.2)Serum albumin; Prothrombin time and international normalized ratio; Individual serum coagulating factor levels; Factor VIII; Factors V and VII; Cell counts and other biochemistry (Table 2.2); Thrombocytopenia; Neutropenia; Anemia; Globulins; Hyponatremia; Accuracy of routine laboratory investigations (Table 2.3); Combination indices or models for detecting cirrhosis (Table 2.4); Specific tests for determining the etiology of liver cirrhosis; Tests for viral hepatitis; Tests for alcoholic liver disease; Tests for primary biliary cirrhosis.
  • Tests for primary sclerosing cholangitisTests for hereditary hemochromatosis; Transferrin saturation; Plasma ferritin level; Tests for Wilson's disease; Serum ceruloplasmin; Serum copper; Urine copper excretion; Tests for alpha-1 antitrypsin deficiency; Conclusions; References; 3. Diagnostic imaging modalities; Ultrasonography-based approaches; Grayscale and Doppler US; Contrast-enhanced ultrasonography; Measurement of liver stiffness: transient elastography, acoustic radiation force impulse, supersonic shear-wave elastography, and real-time elastography; CT- and MRI-based approaches.
  • Morphologic changesHemodynamic changes; MR elastography; Other imaging techniques; References; 4. Histology/pathology; Introduction; Cirrhosis: a pathologic spectrum; Fibrosis: extracellular accumulation of matrix components; Vascular changes; Parenchymal nodules: etiologic features; Cirrhosis: an evolving concept; Cirrhosis: a preneoplastic condition; Cirrhosis: a place for biopsy?; References; 5. Fibrosis and fibrogenesis; Introduction; Mechanism of liver fibrosis in hepatitis B and C; Diagnosis of liver fibrosis by imaging; Diagnosis of liver fibrosis by laboratory tests.