Predictive toxicology : from vision to reality /
Tailored to the needs of drug developers, this one-stop reference for medicinal chemists covers all the latest developments in the field of predictive toxicology and its applications in safety assessment. With a keen emphasis on novel approaches, the topics have been tackled by selected expert scien...
| Άλλοι συγγραφείς: | , , , , |
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| Μορφή: | Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Weinheim :
Wiley-VCH,
[2014]
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| Σειρά: | Methods and principles in medicinal chemistry.
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| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Introduction to Predictive Toxicology Tools and Methods / Laura Suter-Dick, Friedlieb Pfannkuch
- Toxicology : Current Approaches and Future Perspectives to Predict Toxic Effects with Computational Tools / Thomas Steger-Hartmann
- Approaches: Data Management : Bioinformatics / Arnd Brandenburg, Hans Gmuender, Timo Wittenberger
- Role of Modeling and Simulation in Toxicology Prediction / Antje-Christine Walz, Hans Peter Grimm, Christophe Meille, Antonello Caruso, Neil Parrott, Thierry Lave
- Genomic Applications for Assessing Toxicities of Liver and Kidney Injury / Philip Hewitt, Esther Johann
- Use of Toxicogenomics for Mechanistic Characterization of Hepatocarcinogens in Shorter Term Studies / Heidrun Ellinger-Ziegelbauer
- Discovery and Application of Novel Biomarkers / Timothy W Gant, Emma L Marczylo, Martin O Leonard
- Predictive Toxicology: Genetics, Genomics, Epigenetics, and Next-Generation Sequencing in Toxicology / Tobias Heckel, Laura Suter-Dick
- Biomarkers as Tools for Predictive Safety Assessment: Novel Markers of Drug-Induced Kidney Injury / Angela Mally
- The Use of Renal Cell Culture for Nephrotoxicity Investigations / Anja Wilmes, Paul Jennings
- The Zebrafish Model in Toxicology / Natalie Mesens
- Predictive Method Development: Challenges for Cosmetics and Genotoxicity as a Case Study / Gladys Ouedraogo, Fabrice Nesslany, Sophie Simar, Smail Talahari, Doris Lagache, Eric Vercauteren, Lauren Nakab, Astrid Mayoux, Brigitte Faquet, Nicole Flamand
- Using Pluripotent Stem Cells and Their Progeny as an Model to Assess (Developmental) Neurotoxicity / Lisa Hoelting, Marcel Leist, Luc Stoppini
- Stem Cell-Based Methods for Identifying Developmental Toxicity Potential / Jessica A Palmer, Robert E Burrier, Laura A Egnash, Elizabeth LR Donley
- Immunogenicity of Protein Therapeutics: Risk Assessment and Risk Mitigation / Harald Kropshofer
- Regulatory Aspects / Beatriz Silva Lima.
