Conceptual background and bioenergetic/mitochondrial aspects of oncometabolism.

Conceptual background and bioenergetic/mitochondrial aspects of oncometabolism. Volume 542 /

Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Galluzzi, Lorenzo (Επιμελητής έκδοσης), Kroemer, Guido (Επιμελητής έκδοσης)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Amsterdam ; Boston : Elsevier/Academic Press, 2014.
Έκδοση:First edition.
Σειρά:Methods in enzymology ; volume 542.
Θέματα:
Clinical enzymology.
Tumors > Growth.
Mitochondrial pathology.
Cancer cells > Growth.
HEALTH & FITNESS > Diseases > General.
MEDICAL > Clinical Medicine.
MEDICAL > Diseases.
MEDICAL > Evidence-Based Medicine.
MEDICAL > Internal Medicine.
Mitochondria > physiology.
Neoplasms > metabolism.
Electronic books.
Διαθέσιμο Online:Full Text via HEAL-Link
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245 0 0 |a Conceptual background and bioenergetic/mitochondrial aspects of oncometabolism.  |n Volume 542 /  |c edited by Lorenzo Galluzzi and Guido Kroemer. 
250 |a First edition. 
264 1 |a Amsterdam ;  |a Boston :  |b Elsevier/Academic Press,  |c 2014. 
264 4 |c ©2014 
300 |a 1 online resource (xxiii, 509 pages, 30 pages of plates) :  |b illustrations (some color). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in enzymology,  |x 0076-6879 ;  |v v. 542 
504 |a Includes bibliographical references and indexes. 
505 0 0 |t Metabolic alterations of cancer cells /  |r Marco Sciacovelli, Edoardo Gaude, Mika Hilvo, and Christian Frezza -- Autophagy and cancer metabolism /  |r Juliet Goldsmith, Beth Levine, and Jayanta Debnath --  |t Regulation of cancer metabolism by oncogenes and tumor suppressors /  |r Raffaella Iurlaro, Clara Lucía León-Annicchiarico, and Cristina Muñoz-Pinedo --  |t Cross talk between cell death regulation and metabolism /  |r Simone Fulda --  |t Techniques to monitor glycolysis /  |r Tara TeSlaa and Michael A. Teitell --  |t Measurement of enolase activity in cell lysates /  |r Keigo Fukano and Kazuhiro Kimura /  |t Extracellular flux analysis to monitor glycolytic rates and mitochondrial oxygen consumption /  |r Martin Pelletier, Leah K. Billingham, Madhu Ramaswamy, and Richard M. Siegel --  |t Conventional techniques to monitor mitochondrial oxygen consumption /  |r Hélène Simonnet, Arnaud Vigneron, and Jacques Pouysségur --  |t Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry /  |r Gerhard Krumschnabel, Andrea Eigentler, Mario Fasching, and Erich Gnaiger --  |t Kinetic analysis of local oxygenation and respiratory responses of mammalian cells using intracellular oxygen-sensitive probes and time-resolved fluorometry /  |r Alexander V. Zhdanov, Ruslan I. Dmietriev, James Hynes, and Dmitri B. Papkovsky --  |t Cell-based measurements of mitochondrial function in human subjects /  |r Ju-Gyeong Kang, Ping-yuan Wang, and Paul M. Hwang --  |t Use of chemical probes to detect mitochondrial ROS by flow cytometry and spectrofluorometry /  |r Jing Chen and Clayton E. Mathews --  |t Methods to monitor ROS production by fluorescence microscopy and fluorometry /  |r Aleksandra Wojtala, Massimo Bonora, Dominika Malinska, Paolo Pinton, Jerzy Duszynski, and Mariusz R. Wieckowski --  |t Genetically encoded redox sensor /  |r Wai Kan Chiu, Atif Towheed, and Michael J. Palladino --  |t Use of genetically encoded sensors to monitor cytosolic ATP/ADP ratio in living cells /  |r Andrei I. Tarasov and Guy A. Rutter --  |t Methods to monitor and compare mitochondrial and glycolytic ATP production /  |r Simone Patergnani, Federica Baldassari, Elena De Marchi, Agnieszka Karkucinska-Wieckowska, Mariusz R. Wieckowski, and Paolo Pinton --  |t Measurement of ADP-ATP exchange in relation to mitochondrial transmembrane potential and oxygen consumption /  |r Christos Chinopoulos, Gergely Kiss, Hibiki Kawamata, and Anatoly A. Starkov --  |t Real-time assessment of the metabolic profile of living cells with genetically encoded NADH sensors /  |r Yuzheng Zhao, Yi Yang, and Joseph Loscalzo --  |t 13C isotope-assisted methods for quantifying glutamine metabolism in cancer cells /  |r Jie Zhang, Woo Suk Ahn, Paulo A. Gameiro, Mark A. Keibler, Zhe Zhang, and Gregory Stephanopoulos --  |t Measurement of fatty acid oxidation rates in animal tissues and cell lines /  |r Frank K. Huynh, Michelle F. Green, Timothy R. Koves, and Matthew D. Hirschey --  |t Methods to assess lipid accumulation in cancer cells /  |r Jørgen Sikkeland, Yang Jin, and Fahri Saatcioglu --  |t Analysis of hypoxia-induced metabolic preprogramming /  |r Chendong Yang, Lei Jiang, Huafeng Zhang, Larissa A. Shimoda, Ralph J. Bernardinis, and Gregg L. Semenza. 
520 |a Volume 542 of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This new volume covers research methods providing a theoretical overview on metabolic alterations of cancer cells and a series of protocols that can be employed to study oncometabolism, in vitro, ex vivo and in vivo. Malignant cells exhibit metabolic changes when compared to their normal counterparts, owing to both genetic and epigenetic alterations. Although such a metabolic rewiring has recently been indicated as ""yet another"" general hallmark of ca. 
650 0 |a Clinical enzymology. 
650 0 |a Tumors  |x Growth. 
650 0 |a Mitochondrial pathology. 
650 0 |a Cancer cells  |x Growth. 
650 7 |a HEALTH & FITNESS  |x Diseases  |x General.  |2 bisacsh 
650 7 |a MEDICAL  |x Clinical Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Diseases.  |2 bisacsh 
650 7 |a MEDICAL  |x Evidence-Based Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Internal Medicine.  |2 bisacsh 
650 7 |a Cancer cells  |x Growth.  |2 fast  |0 (OCoLC)fst00845567 
650 7 |a Clinical enzymology.  |2 fast  |0 (OCoLC)fst00864350 
650 7 |a Mitochondrial pathology.  |2 fast  |0 (OCoLC)fst01024022 
650 7 |a Tumors  |x Growth.  |2 fast  |0 (OCoLC)fst01158769 
650 2 |a Mitochondria  |x physiology. 
650 2 |a Neoplasms  |x metabolism. 
655 4 |a Electronic books. 
655 7 |a Electronic books.  |2 lcgft 
700 1 |a Galluzzi, Lorenzo,  |e editor. 
700 1 |a Kroemer, Guido,  |e editor. 
776 0 8 |i Print version:  |t Methods in enzymology. Volume five hundred and forty two, Conceptual background and bioenergetic/mitochondrial aspects of oncometabolism.  |d San Diego, California : Academic Press, ©2014  |h xxiii, 509 pages  |k Methods in enzymology.  |x 0076-6879  |z 9780124166189 
830 0 |a Methods in enzymology ;  |v volume 542.  |x 0076-6879 
856 4 0 |u https://www.sciencedirect.com/science/bookseries/00766879/542  |z Full Text via HEAL-Link 

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