Closed-form solutions for drug transport through controlled-release devices in two and three dimensions /

• Κύριοι συγγραφείς: Simon, Laurent, 1968- (Συγγραφέας), Ospina, Juan, 1965- (Συγγραφέας)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, New Jersey : John Wiley & Sons Inc., [2015]
• Θέματα: Pharmaceutical technology > Methods.; Drug delivery systems.; Drug delivery systems > Mathematical models.; Technology, Pharmaceutical > methods.; Drug Delivery Systems.; Models, Theoretical.; MEDICAL > Pharmacology.; Electronic books.

"Covers the modeling of drug-delivery systems and provides mathematical tools to evaluate and build controlled-release devices"--Provided by publisher.

Πίνακας περιεχομένων:

• TITLE PAGE; COPYRIGHT; TABLE OF CONTENTS; PREFACE; ACKNOWLEDGMENTS; 1 STEADY-STATE ANALYSIS OF A TWO-DIMENSIONAL MODEL FOR PERCUTANEOUS DRUG TRANSPORT; 1.1 SEPARATION OF VARIABLES IN 2-D CARTESIAN COORDINATES; 1.2 MODEL FOR DRUG TRANSPORT ACROSS THE SKIN; 1.3 ANALYTICAL SOLUTION OF THE DIFFUSION MODEL IN 2-D CARTESIAN SYSTEMS; 1.4 SUMMARY; 1.5 APPENDIX: MAPLE, MATHEMATICA, AND MAXIMA CODE LISTINGS; PROBLEMS; REFERENCES; 2 CONSTANT DRUG RELEASE FROM A HOLLOW CYLINDER OF FINITE LENGTH IN TWO DIMENSIONS; 2.1 SEPARATION OF VARIABLES IN 2-D CYLINDRICAL COORDINATES
• 2.2 MODEL FOR DRUG RELEASE FROM A HOLLOW CYLINDER2.3 ANALYTICAL SOLUTION OF THE TRANSPORT MODEL IN 2-D CYLINDRICAL COORDINATES; 2.4 SUMMARY; 2.5 APPENDIX: MAPLE CODE LISTINGS; PROBLEMS; REFERENCES; 3 ANALYSIS OF STEADY-STATE GROWTH FACTOR TRANSPORT THROUGH DOUBLE-LAYERED SCAFFOLDS; 3.1 GOVERNING STEADY-STATE TRANSPORT EQUATIONS; 3.2 SOLUTION PROCEDURE FOR TRANSPORT THROUGH A TWO-LAYERED SCAFFOLD; 3.3 CONCENTRATION PROFILE OF VASCULAR ENDOTHELIAL GROWTH FACTOR IN TWO LAYERS; 3.4 SUMMARY; 3.5 APPENDIX: MAPLE CODE LISTINGS; PROBLEMS; REFERENCES
• 4 STEADY-STATE TWO-DIMENSIONAL DIFFUSION IN A HOLLOW SPHERE4.1 SEPARATION OF VARIABLES AND LEGENDRE POLYNOMIALS IN 2-D SPHERICAL COORDINATES; 4.2 MODEL FOR 2-D DIFFUSION IN A SPHERE; 4.3 ANALYTICAL SOLUTION OF 2-D DIFFUSION IN SPHERICAL COORDINATES; 4.4 SUMMARY; 4.5 APPENDIX: MAPLE, MATHEMATICA, AND MAXIMA CODE LISTINGS; PROBLEMS; REFERENCES; 5 STEADY-STATE THREE-DIMENSIONAL DRUG DIFFUSION THROUGH MEMBRANES FROM DISTRIBUTED SOURCES; 5.1 SEPARATION OF VARIABLES IN 3-D CARTESIAN COORDINATES; 5.2 TRANSPORT ACROSS THE MEMBRANE
• 5.3 ANALYTICAL SOLUTION OF THE DIFFUSION MODEL IN 3-D CARTESIAN SYSTEMS5.4 SUMMARY; 5.5 APPENDIX: MAPLE CODE LISTINGS; PROBLEMS; REFERENCES; 6 CONSTANT DRUG RELEASE FROM A HOLLOW CYLINDER OF FINITE LENGTH IN THREE DIMENSIONS; 6.1 SEPARATION OF VARIABLES IN 3-D CYLINDRICAL COORDINATES; 6.2 MODEL FOR 3-D DRUG RELEASE FROM A HOLLOW CYLINDER; 6.3 ANALYTICAL SOLUTION OF THE TRANSPORT MODEL IN 3-D CYLINDRICAL COORDINATES; 6.4 SUMMARY; 6.5 APPENDIX: MAPLE CODE LISTINGS; PROBLEMS; REFERENCES; 7 SUSTAINED DRUG RELEASE FROM A HOLLOW SPHERE IN THREE DIMENSIONS
• 7.1 METHOD OF GREEN'S FUNCTION IN 3-D SPHERICAL COORDINATES7.2 MODEL FOR MOLECULAR TRANSPORT ACROSS THE WALL OF A HOLLOW SPHERE; 7.3 ANALYTICAL SOLUTION OF THE TRANSPORT MODEL IN 3-D SPHERICAL COORDINATES; 7.4 SUMMARY; 7.5 APPENDIX: MAPLE, MATHEMATICA AND MAXIMA CODE LISTINGS; PROBLEMS; REFERENCES; 8 ANALYSIS OF TRANSIENT GROWTH FACTOR TRANSPORT THROUGH DOUBLE-LAYERED SCAFFOLDS; 8.1 LAPLACE AND FOURIER-BESSEL-BASED METHODS IN 2-D CYLINDRICAL COORDINATES; 8.2 GOVERNING EQUATIONS FOR TRANSPORT THROUGH DOUBLE-LAYERED SCAFFOLDS