Antitargets and drug safety /

With its focus on emerging concerns of kinase and GPCR-mediated antitarget effects, this vital reference for drug developers addresses one of the hot topics in drug safety now and in future. Divided into three major parts, the first section deals with novel technologies and includes the utility of a...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Urbán, László, Patel, Vinod F., Vaz, Roy J.
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Weinheim : Wiley-VCH, 2015.
Σειρά:Methods and principles in medicinal chemistry ; v. 66.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Περιγραφή
Περίληψη:With its focus on emerging concerns of kinase and GPCR-mediated antitarget effects, this vital reference for drug developers addresses one of the hot topics in drug safety now and in future. Divided into three major parts, the first section deals with novel technologies and includes the utility of adverse event reports to drug discovery, the translational aspects of preclinical safety findings, broader computational prediction of drug side-effects, and a description of the serotonergic system. The main part of the book looks at some of the most common antitarget-mediated side effects, focusing.
Φυσική περιγραφή:1 online resource (1266 pages).
Βιβλιογραφία:Includes bibliographical references and index.
ISBN:9783527673643
3527673644
9783527673674
3527673679
DOI:10.1002/9783527673643