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| LEADER |
03649nam a2200721 4500 |
| 001 |
ocn905991359 |
| 003 |
OCoLC |
| 005 |
20170124070336.8 |
| 006 |
m o d |
| 007 |
cr cnu---unuuu |
| 008 |
150328s2015 gw ob 001 0 eng d |
| 040 |
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|a EBLCP
|b eng
|e rda
|e pn
|c EBLCP
|d OCLCO
|d RECBK
|d OCLCQ
|d YDXCP
|d OCLCO
|d N$T
|d IDEBK
|d DG1
|d OCLCF
|d COO
|d N$T
|d QGK
|d DEBBG
|d KSU
|d GrThAP
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| 019 |
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|a 910983561
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| 020 |
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|a 9783527673049
|q electronic bk.
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| 020 |
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|a 3527673040
|q electronic bk.
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| 020 |
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|a 9783527673025
|q electronic bk.
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| 020 |
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|a 3527673024
|q electronic bk.
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| 020 |
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|z 9783527673056
|q electronic bk.
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| 020 |
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|z 3527673059
|q electronic bk.
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| 020 |
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|a 9783527673032
|q electronic bk.
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| 020 |
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|a 3527673032
|q electronic bk.
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| 020 |
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|z 9783527335824
|q (print ;
|q alk. paper)
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| 020 |
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|z 352733582X
|q (print ;
|q alk. paper)
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| 024 |
7 |
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|a 10.1002/9783527673025
|2 doi
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| 029 |
1 |
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|a GBVCP
|b 83642624X
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| 029 |
1 |
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|a DEBBG
|b BV043397671
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| 035 |
|
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|a (OCoLC)905991359
|z (OCoLC)910983561
|
| 050 |
|
4 |
|a RM301.25
|b .T44 2015eb
|
| 060 |
|
4 |
|a W1
|b ME9613h v.65 2015
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| 060 |
|
4 |
|a QV 745
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| 072 |
|
7 |
|a MED
|x 071000
|2 bisacsh
|
| 082 |
0 |
4 |
|a 615.19
|2 23
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| 049 |
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|a MAIN
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| 245 |
0 |
0 |
|a Thermodynamics and kinetics of drug binding /
|c edited by György M. Keserü and David C. Swinney.
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| 264 |
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1 |
|a Weinheim, Germany :
|b Wiley-VCH Verlag GmbH & Co. KGaA,
|c [2015]
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| 300 |
|
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|a 1 online resource (xxiii, 334 pages) :
|b illustrations (some color)
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| 336 |
|
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|a text
|b txt
|2 rdacontent
|
| 337 |
|
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Methods and principles in medicinal chemistry ;
|v volume 65
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| 504 |
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|a Includes bibliographical references and index.
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| 520 |
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|a "This practical reference for medicinal and pharmaceutical chemists combines the theoretical background with modern methods as well as applications from recent lead finding and optimization projects. Divided into two parts on the thermodynamics and kinetics of drug-receptor interaction, the text provides the conceptual and methodological basis for characterizing binding mechanisms for drugs and other bioactive molecules. It covers all currently used methods, from experimental approaches, such as ITC or SPR, right up to the latest computational methods. Case studies of real-life lead or drug development projects are also included so readers can apply the methods learned to their own projects. Finally, the benefits of a thorough binding mode analysis for any drug development project are summarized in an outlook chapter written by the editors."--
|c Publisher's info.
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| 588 |
0 |
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|a Description based on print version record.
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| 650 |
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0 |
|a Drug development.
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| 650 |
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0 |
|a Binding sites (Biochemistry)
|x Thermodynamics.
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| 650 |
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0 |
|a Pharmacokinetics.
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| 650 |
|
7 |
|a MEDICAL / Pharmacology
|2 bisacsh
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| 650 |
|
7 |
|a Binding sites (Biochemistry)
|x Thermodynamics.
|2 fast
|0 (OCoLC)fst00831877
|
| 650 |
|
7 |
|a Drug development.
|2 fast
|0 (OCoLC)fst00898670
|
| 650 |
|
7 |
|a Pharmacokinetics.
|2 fast
|0 (OCoLC)fst01060250
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| 650 |
1 |
2 |
|a Drug Discovery.
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| 650 |
1 |
2 |
|a Receptors, Drug.
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| 650 |
2 |
2 |
|a Ligands.
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| 650 |
2 |
2 |
|a Thermodynamics.
|
| 650 |
2 |
2 |
|a Pharmacokinetics.
|
| 655 |
|
4 |
|a Electronic books.
|
| 655 |
|
0 |
|a Electronic books.
|
| 700 |
1 |
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|a Keserü, G. M.,
|e editor.
|
| 700 |
1 |
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|a Swinney, David Carl,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Thermodynamics and kinetics of drug binding
|z 9783527335824
|w (OCoLC)910103973
|
| 830 |
|
0 |
|a Methods and principles in medicinal chemistry ;
|v v. 65.
|
| 856 |
4 |
0 |
|u https://doi.org/10.1002/9783527673025
|z Full Text via HEAL-Link
|
| 994 |
|
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|a 92
|b DG1
|
