Randomization in clinical trials : theory and practice /

• Main Author: Rosenberger, William F.
• Other Authors: Lachin, John M., 1942-
• Format: eBook
• Language: English
• Published: Hoboken, New Jersey : Wiley, c2016.
• Series: Wiley series in probability and statistics.
• Subjects: Clinical trials.; Sampling (Statistics); HEALTH & FITNESS / Holism; HEALTH & FITNESS / Reference; MEDICAL / Alternative Medicine; MEDICAL / Atlases; MEDICAL / Essays; MEDICAL / Family & General Practice; MEDICAL / Holistic Medicine; MEDICAL / Osteopathy; Randomized Controlled Trials as Topic.; Electronic books.

Table of Contents:

• Randomization and the clinical trial
• Issues in the design of clinical trials
• Randomization for balancing treatment assignments
• Balancing on known covariates
• The effects of unobserved covariates
• Selection bias
• Randomization as a basis for inference
• Inference for stratified, blocked, and covariate-adjusted analyses
• Randomization in practice
• Response-adaptive randomization
• Inference for response-adaptive randomization
• Response-adaptive randomization in practice
• Some useful results in large sample theory
• Large sample inference for complete and restricted randomization
• Large sample inference for response-adaptive randomization.