Attrition in the pharmaceutical industry : reasons, implications, and pathways forward /

• Άλλοι συγγραφείς: Alex, Alexander A. (Επιμελητής έκδοσης), Harris, C. John (Επιμελητής έκδοσης), Smith, Dennis A. (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, New Jersey : John Wiley & Sons, 2015.
• Θέματα: Pharmaceutical industry > Management.; Pharmaceutical industry > Capital productivity.; Industrial efficiency.; Drug development.; MEDICAL / Pharmacology; Electronic books.

Πίνακας περιεχομένων:

• Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis
• Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop
• Attrition in phase I / Dennis A. Smith and Thomas A. Baillie
• Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith
• Post-marketing attrition / Dennis A. Smith
• Influence of the regulatory environment on attrition / Robert T. Clay
• Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt
• Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy
• Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams
• In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis
• Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale
• Impact of investment strategies, organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton.