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05509nam a2200577 4500 |
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ocn931805440 |
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OCoLC |
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20180501122028.0 |
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m o d |
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151208s2015 maua ob 001 0 eng d |
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|a YDXCP
|b eng
|e pn
|c YDXCP
|d IDEBK
|d N$T
|d OPELS
|d CDX
|d OCLCF
|d EBLCP
|d FDA
|d OCLCO
|d OCLCQ
|d DEBBG
|e rda
|d MEU
|d GrThAP
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|a 930788485
|a 930996335
|a 932337741
|a 958083794
|a 958392279
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|a 9780128013762
|q (electronic bk.)
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|a 0128013761
|q (electronic bk.)
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|a 9780128012789
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|a 0128012781
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|a (OCoLC)931805440
|z (OCoLC)930788485
|z (OCoLC)930996335
|z (OCoLC)932337741
|z (OCoLC)958083794
|z (OCoLC)958392279
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|a QP801.C27
|b I58 2015eb
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|a MED
|x 071000
|2 bisacsh
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|a 615.7/827
|2 23
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|a TEFA
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|a Endocannabinoids /
|c edited by Loren Parsons, Matthew Hill.
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|a First edition.
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| 264 |
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1 |
|a Waltham, MA :
|b Academic Press,
|c 2015.
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| 300 |
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|a 1 online resource (xii, 354 pages :
|b illustrations).
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a International review of neurobiology ;
|v volume 125
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| 546 |
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|a Text in English.
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| 588 |
0 |
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|a Online resource; title from PDF title page (EBSCO, viewed December 22, 2015).
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| 504 |
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|a Includes bibliographical references and index.
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| 520 |
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|a Endocannabinoids, the latest volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into the neurobiology of migraines. It reviews the current knowledge and understanding in the field, and provides a starting point for researchers and practitioners entering the field.
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| 500 |
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|a "Academic Press is an imprint of Elsevier."
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| 505 |
0 |
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|a Front Cover; Endocannabinoids; Copyright; Contents; Contributors; Preface; Chapter One: The Endocannabinoid Signaling System in the CNS: A Primer; 1. Introduction; 2. The Endocannabinoids; 2.1. Definitions; 2.2. Mechanisms of AEA Biosynthesis; 2.2.1. Precursor Synthesis; 2.2.2. NAPE Conversion to NAE: NAPE-PLD; 2.2.3. NAPE Conversion to NAE: Multienzyme Pathways; 2.2.4. AEA Synthesis from AA; 2.2.5. Summary; 2.3. Mechanisms of AEA Hydrolysis; 2.3.1. Fatty Acid Amide Hydrolase; 2.3.2. NAE-Hydrolyzing Acid Amidase: A Peripheral AEA Hydrolase; 2.4. Mechanisms of 2-AG Biosynthesis.
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| 505 |
8 |
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|a 2.4.1. Diacylglycerol Lipase2.4.2. Mechanisms of DAG Synthesis; 2.5. Mechanisms of 2-AG Catabolism; 2.5.1. Monoacylglycerol Lipase; 2.5.2. Other Enzymes that Hydrolyze 2-AG in the Brain; 2.5.3. Contribution of 2-AG to AA Concentrations; 2.6. Other Inactivation Mechanisms for AEA and 2-AG; 2.6.1. Uptake, Accumulation, and Sequestration; 2.6.2. Oxygenation of the Arachidonate Backbone; 3. Endocannabinoid Receptors; 3.1. Introduction; 3.2. CB1 Cannabinoid Receptors; 3.2.1. CB1R Signaling; 3.2.2. CB1R Pharmacology; 4. CB1R and Retrograde Regulation of Synaptic Activity; 4.1. The Basic Paradigms.
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| 505 |
8 |
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|a 4.1.1. Short-Term Depression of Synaptic Transmission4.1.2. Long-Term Depression of Transmission; 5. Summary; Acknowledgments; References; Chapter Two: Evidence for a Role of Adolescent Endocannabinoid Signaling in Regulating HPA Axis Stress Responsivity and E ... ; 1. Adolescence and Pubertal Maturation; 2. The Neurobiology of Stress; 3. Adolescent HPA Axis Development; 4. The Developmental Influence of Gonadal Hormones on the HPA Axis; 5. The Endocannabinoid System; 6. Endocannabinoid System Regulation of the HPA Axis in Adulthood; 7. Ontogeny of the Endocannabinoid System.
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| 505 |
8 |
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|a 8. Adolescent HPA Axis Function: A Regulatory Role for the Endocannabinoid System?8.1. Adolescent Stress Exposure Modulates Corticolimbic Endocannabinoid Signaling; 8.2. Adolescent Cannabinoid Exposure Modifies Adult Stress-Induced HPA Axis Activity; 8.3. Long-Term Consequences of Adolescent Endocannabinoid System Dysregulation on the Developing Brain and Behavior; 9. Concluding Remarks; Acknowledgments; References; Chapter Three: The Endocannabinoid System and Its Role in Regulating the Intrinsic Neural Circuitry of the Gastrointestin ... ; 1. Introduction.
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| 505 |
8 |
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|a 2. The Enteric Nervous System and the Brain-Gut Axis2.1. The Structure of the ENS; 3. The Endocannabinoid System; 3.1. Cannabinoid Receptors and Their Ligands; 3.2. Cannabinoid Receptors in the ENS; 3.3. Endocannabinoid Synthesis; 3.4. 2-AG Synthesis and Degradation; 3.5. Anandamide Synthesis and Degradation; 4. Endocannabinoid Signaling Mechanisms; 4.1. Endocannabinoid Transport Mechanisms; 5. Other Receptors, Agonists, and Antagonists; 5.1. Phytocannabinoids; 5.2. Peptide Endocannabinoids; 5.3. Transient Receptor Potential Vanilloid 1; 5.4. Virodhamine, an Endogenous CB1 Antagonist.
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| 650 |
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0 |
|a Cannabinoids
|x Physiological effect.
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| 650 |
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0 |
|a Pharmacology, Experimental.
|
| 650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
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| 650 |
|
7 |
|a Cannabinoids
|x Physiological effect.
|2 fast
|0 (OCoLC)fst00845735
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| 650 |
|
7 |
|a Pharmacology, Experimental.
|2 fast
|0 (OCoLC)fst01060280
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| 655 |
|
4 |
|a Electronic books.
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| 700 |
1 |
|
|a Parsons, Loren,
|e editor.
|
| 700 |
1 |
|
|a Hill, Matthew,
|d 1980-
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|a Parsons, Loren.
|t Endocannabinoids.
|d Saint Louis : Elsevier Science, ©2015
|
| 830 |
|
0 |
|a International review of neurobiology ;
|v v. 125.
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| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/00747742/125
|z Full Text via HEAL-Link
|
