The molecular basis of drug addiction /

This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Rahman, Shafiqur, 1963- (Επιμελητής έκδοσης)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Cambridge, MA : Academic Press is an imprint of Elsevier, [2016]
Σειρά:Progress in molecular biology and translational science ; v. 137.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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245 0 4 |a The molecular basis of drug addiction /  |c edited by Shafiqur Rahman. 
264 1 |a Cambridge, MA :  |b Academic Press is an imprint of Elsevier,  |c [2016] 
264 4 |c Ã2016 
300 |a 1 online resource 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Progress in Molecular Biology and Translational Science ;  |v v. 137 
588 0 |a Online resource; title from PDF title page (EBSCO, viewed February 11, 2016) 
504 |a Includes bibliographical references and index. 
520 |a This volume of Progress in Molecular Biology and Translational Science focuses on the molecular basis of drug addiction. 
505 0 |a Cover; Title page; Copyright page ; Contents ; Contributors; Preface; Chapter One -- Molecular Mechanism: ERK Signaling, Drug Addiction, and Behavioral Effects ; Abstract; 1 Introduction; 2 ERK Signaling Pathway; 3 ERK Signaling and Drug Addiction; 3.1 Cocaine; 3.2 Amphetamine; 3.3 Methamphetamine; 3.4 Marijuana; 3.5 Nicotine; 3.6 Alcohol (Ethanol); 4 Conclusions and Future Directions; Acknowledgment; References; Chapter Two -- Ethanol-Associated Changes in Glutamate Reward Neurocircuitry: A Minireview of Clinical and Preclinical Genetic Findings ; Abstract; 1 Alcoholism and Genetics 
505 8 |a 2 Central Glutamatergic Activity2.1 Metabotropic Glutamate Receptors ; 2.2 Ionotropic Glutamate Receptors ; 2.3 Glutamate Transporters and Carriers ; 2.4 Glutamate Synthesis and Metabolism ; 2.5 Glutamate and the Postsynaptic Density ; 3 Central Glutamate Activity and Alcohol Dependence; 3.1 Alcohol's Effects on Glutamate Activity and Extracellular Levels; 3.2 Metabotropic Glutamate Receptors and Alcohol; 3.3 Ionotropic Glutamate Receptors and Alcohol; 3.4 Glutamate Transporters/Carriers and Alcohol; 3.5 Glutamate-Associated Enzyme Activity and Alcohol 
505 8 |a 3.6 The Postsynaptic Density and Alcohol4 Glutamate-Associated Genetic Variations and Alcoholism; 5 Alcohol and Glutamate Gene Expression; 6 Alcohol-Associated Changes in Gene/Protein Expression of P Rats; 6.1 Metabotropic Glutamate Receptor Expression Differences ; 6.2 Ionotropic Glutamate Receptor Expression Differences ; 6.3 Expression Differences for Glutamate Transporters, Enzymes, and Postsynaptic Density ; 7 Conclusions; Acknowledgments; References; Chapter Three -- S-Glutathionylation and Redox Protein Signaling in Drug Addiction ; Abstract; 1 Introduction ; 2 Oxidative Stress 
505 8 |a 3 S-Glutathionylation of Proteins Occurs in Response to Oxidative Stress 4 S-Glutathionylation of Proteins is a Redox-Sensitive Signaling Mechanism in Cells ; 5 S-Glutathionylation in Addiction-Related Protein Signaling ; 5.1 Drug Addiction, Dopamine, and Oxidative Stress ; 5.2 Altered Neurotransmission in Response to Ethanol, Cocaine, and Opioids Share Common Signaling Mechanisms ; 6 S-Glutathionylation of PKA, PKC, Cdk5, and Actin May Influence Drug Behavior ; 7 S-Glutathionylation in Alcohol Addiction ; 7.1 Ethanol Metabolism Increases ROS Production 
505 8 |a 7.2 Increased ROS Production May Contribute to the Behavioral Effects of Ethanol 7.3 Protein S-Glutathionylation in Response to Ethanol ; 8 S-Glutathionylation in Cocaine Addiction ; 8.1 Cocaine Metabolism Increases ROS Production ; 8.2 Increased ROS Production May Contribute to the Behavioral Effects of Cocaine ; 8.3 Protein S-Glutathionylation in Response to Cocaine ; 9 S-Glutathionylation in Heroin Addiction ; 9.1 Heroin Metabolism Increases ROS Production ; 9.2 Increased ROS Production May Contribute to the Behavioral Effects of Heroin 
650 0 |a Substance abuse  |x Physiological aspects. 
650 0 |a Drug abuse  |x Molecular aspects. 
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650 7 |a MEDICAL / Internal Medicine  |2 bisacsh 
650 7 |a Drug abuse  |x Molecular aspects.  |2 fast  |0 (OCoLC)fst00898510 
650 7 |a Substance abuse  |x Physiological aspects.  |2 fast  |0 (OCoLC)fst01136793 
655 0 |a Electronic books. 
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700 1 |a Rahman, Shafiqur,  |d 1963-  |e editor. 
776 0 8 |i Print version:  |a Rahman, Shafiqur  |t The Molecular Basis of Drug Addiction  |d : Elsevier Science,c2016  |z 9780128037867 
830 0 |a Progress in molecular biology and translational science ;  |v v. 137. 
856 4 0 |u https://www.sciencedirect.com/science/bookseries/18771173/137  |z Full Text via HEAL-Link