Essays on developmental biology. Part A /

• Άλλοι συγγραφείς: Wassarman, Paul M. (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cambridge, MA : Academic Press, 2016.
• Σειρά: Current topics in developmental biology ; v. 116.
• Θέματα: Developmental biology.; Morphogenesis.; SCIENCE / Life Sciences / Anatomy & Physiology; Electronic books.

Πίνακας περιεχομένων:

• Front Cover; Essays on Developmental Biology, Part A; Copyright; Contents; Contributors; Preface; Chapter One: Seeing is Believing, or How GFP Changed My Approach to Science; 1. From Fly Mutants to Developmental Control Genes; 2. From Mutants to Cell Behavior; 3. From Flies to Fish; 4. From GFP to GFP Binders; 5. The Crispr Revolution or Bringing It All Together; Acknowledgments; References; Chapter Two: The Notch-Mediated Proliferation Circuitry; 1. Notch Can Have Opposing Effects on Proliferation; 2. Notch Affects Proliferation in Both Cell-Autonomous and Non-Cell-Autonomous Manners
• 3. Notch and Proliferation in Oncogenesis4. Proliferative Effects of Notch in Stem Cells; 5. Notch Synergies in Proliferation; 6. A Notch-JNK Signaling Axis Couples Proliferation and Invasiveness; 7. Notch Synergies in Oncogenesis: A Hypothesis; References; Chapter Three: Defining the Path from Stem Cells to Differentiated Tissue; References; Chapter Four: Neuregulin/ErbB Signaling in Developmental Myelin Formation and Nerve Repair; 1. Introduction; 2. Schwann Cell Precursors; 3. Entry into the Myelination Program; 4. Nrg1 and Other Extrinsic Signals that Control Myelination
• 5. Proteolytic Processing is Rate Limiting for Nrg1 Activity and Function6. Rates of Protein Synthesis Control the End ofMyelination and Myelin Thickness; 7. Nrg1 and Remyelination After Injury; Acknowledgments; References; Chapter Five: Oocyte Meiotic Spindle Assembly and Function; 1. Introduction; 2. Maintain Parity or Pare Down: Mitotic Versus Meiotic Cell Division; 3. Centrosomes: The Stars of Mitotic Spindle Poles; 4. The Curious Structure of (Some) Oocyte Meiotic Spindles: Acentriolar Poles; 5. The Curious Structure of Oocyte Meiotic Spindles, Part 2: Tiled Microtubules
• 6. Acentriolar Oocyte Meiotic Spindle Assembly: Microtubule Origins7. Acentriolar Oocyte Meiotic Spindle Assembly, Part 2: Pole Composition; 8. Acentriolar Oocyte Meiotic Spindle Assembly, Part 3: Pole Assembly; 9. Kinetochore Function and Pole Coalescence; 10. A Pushy View of Kinetochore Function and Chromosome Dynamics During Oocyte Meiosis; 11. An Alternative Model for Chromosome Movements in C. elegans Oocytes: Sides Matter; 12. Advancing Our Understanding of Oocyte Meiotic Spindle Assembly: Genetics and Live Cell Imaging; Acknowledgments; References
• Chapter Six: Self-Organization of Spatial Patterning in Human Embryonic Stem Cells1. Introduction; 2. Self-Organization of Human Embryonic Germ Layers; 3. Self-Organization of Neural Rosettes; 4. Challenges and Future Directions; References; Chapter Seven: The Neural Crest Migrating into the Twenty-First Century; 1. Introduction; 2. A Brief History; 3. Neural Crest Migration; 4. Gene Regulatory Network Controlling Neural Crest Formation; 5. Differentiation of Neural Crest Cells into Multiple Lineages; 6. Evolution of the Neural Crest