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ocn948604238 |
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OCoLC |
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20180501122030.0 |
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m o d |
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cr cnu|||unuuu |
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160503s2016 mau o 000 0 eng d |
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|a 949883225
|a 953862896
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|a 9780128033265
|q electronic bk.
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|a 0128033266
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|a 9780128033197
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|a 573.1/55
|2 23
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|a TEFA
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| 245 |
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|a Hematopoiesis /
|c edited by Emery H. Bresnick.
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|a Cambridge, MA :
|b Academic Press is an imprint of Elsevier,
|c 2016.
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| 300 |
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|a 1 online resource.
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Current topics in developmental biology ;
|v volume 118
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|a Online resource; title from PDF title page (ScienceDirect, viewed May 9, 2016).
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|a Front Cover; Hematopoiesis; Copyright; Contents; Contributors; Preface; Chapter One: Regulation of Blood Stem Cell Development; 1. Introduction; 1.1. HSC Generation; 1.2. Tracking Hematopoietic Cell Generation from Embryonic Endothelium; 1.3. Regulation of Hemogenic Endothelium; 1.4. Hemogenic Transcriptional Program; 1.5. Reprogramming; References; Chapter Two: Hematopoietic Stem Cell and Its Bone Marrow Niche; 1. Introduction; 2. Evolution of the Stem Cell Niche Concept; 3. Location Matters; 4. Cellular Participants in the Bone Marrow Microenvironment; 4.1. Osteolineage Cells
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|a 4.2. Perivascular Cells4.3. Endothelial Cells; 4.4. Adipocytes; 4.5. Macrophages; 5. The Sympathetic Nervous System; 6. HSC Mobilization from the BM Niche; 7. Niche of Hematopoietic Malignancies; 8. Perspectives; References; Chapter Three: The Hematopoietic Stem and Progenitor Cell Cistrome: GATA Factor-Dependent cis-Regulatory Mechanisms; 1. cis-Regulatory Mechanisms; 2. GATA Factor Interactions with DNA and Chromatin; 2.1. Sequence Requirements; 2.2. Genomic and Bioinformatics Analysis; 2.3. Discovery and Validation of Enhancers Controlling HSPCs
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|a 3. Components of Scl/TAL1 and GATA Factor Complexes at E-box-GATA Elements3.1. LMO2; 3.2. LDB1; 3.3. KLF1; 3.4. SWI/SNF Chromatin-Remodeling Complex; 3.5. Single-Stranded DNA-Binding Proteins; 4. HSPC Cistrome; 5. Perspective; References; Chapter Four: ETS Transcription Factor ETV2/ER71/Etsrp in Hematopoietic and Vascular Development; 1. Introduction; 2. Etv2 Is Transiently Expressed in the Hemangiogenic Progenitors; 3. ETV2 Is Sufficient to Induce Hematopoietic and Endothelial Cell Formation; 4. Nonredundant and Transient Role of ETV2 in Hematopoietic and Endothelial Cell Formation
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|a 5. ETV2, VEGF, and FLK1 in Hematopoietic and Endothelial Cell Formation6. ETV2 Regulates Hemangiogenic versus Cardiac Mesoderm Outcome; 7. ETS Hierarchy and ETS Switching Mechanisms in Hematopoietic and Vascular Development; 8. ETV2 in Definitive Hematopoietic Program and Function; 9. Regulation of Etv2 Expression; 10. Closing Thoughts and Future Directions; Acknowledgments; References; Chapter Five: Taking the Leap: Runx1 in the Formation of Blood from Endothelium; 1. The Three Waves of Blood Cell Formation; 2. The Role of Runx1 in the Formation of Embryonic Progenitors and HSCs
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|a 3. The Temporal Requirement for Runx1 in Hemogenic Endothelium4. Downstream Runx1 Targets That Execute the Endothelial to Hematopoietic Cell Transition; 5. Epigenetic Regulation by Runx1; 6. Cis-Acting Sequences Regulating Runx1 Transcription; 7. The Gene Regulatory Network Upstream of Runx1; 8. Signaling Pathways Regulating Runx1 Expression in the Aorta; 8.1. Notch Signaling; 8.2. Fibroblast Growth Factor and Bone Morphogenic Protein Signaling; 9. Conclusions and Future Directions; References; Chapter Six: SCL/TAL1 in Hematopoiesis and Cellular Reprogramming; 1. Introduction
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| 650 |
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|a Hematopoiesis.
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| 650 |
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7 |
|a SOCIAL SCIENCE / Anthropology / Physical
|2 bisacsh
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| 650 |
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7 |
|a Hematopoiesis.
|2 fast
|0 (OCoLC)fst00954922
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| 655 |
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|a Electronic books.
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|a Electronic books.
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| 700 |
1 |
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|a Bresnick, Emery H.,
|e editor.
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| 776 |
0 |
8 |
|i Print version:
|a Bresnick, Emery
|t Hematopoiesis
|d : Elsevier Science,c2016
|z 9780128033197
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| 830 |
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0 |
|a Current topics in developmental biology ;
|v v. 118.
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| 856 |
4 |
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|u https://www.sciencedirect.com/science/bookseries/00702153/118
|z Full Text via HEAL-Link
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