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160603s2016 mau o 000 0 eng d |
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|a IDEBK
|b eng
|e pn
|c IDEBK
|d N$T
|d EBLCP
|d YDXCP
|d CBC
|d OPELS
|d OCLCF
|d FDA
|d OCLCO
|d OCLCQ
|d UPM
|d OTZ
|d OCLCQ
|d D6H
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|c (S
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|a 951032891
|a 951222972
|a 951433398
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|a 0128036478
|q (electronic bk.)
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|a 9780128036471
|q (electronic bk.)
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|a 0128036192
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|a 9780128036198
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|a (OCoLC)951075071
|z (OCoLC)951032891
|z (OCoLC)951222972
|z (OCoLC)951433398
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|a QH603.I54
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|a SCI
|x 056000
|2 bisacsh
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|a 571.6/4
|2 23
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|a TEFA
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|a Big on BK :
|b current insights into the function of large conductance voltage- and Ca2+- activated K+ channels at the molecular, cellular and systemic levels /
|c edited by Candice Contet.
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|a Cambridge, MA :
|b Academic Press is an imprint of Elsevier,
|c 2016.
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|a 1 online resource (552).
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a International review of neurobiology ;
|v volume 128
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|a Print version record.
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|6 880-01
|a Front Cover; Big on BK: Current Insights into the Function of Large Conductance Voltage- and Ca2+-Activated K+ Channels at the Molecular ... ; Copyright; Contents; Contributors; Preface; Chapter One: Biophysics of BK Channel Gating; 1. Introduction; 2. Voltage-Dependent Gating in BK Channels; 2.1. Our Current Understanding of Voltage-Dependent Channel Gating; 2.2. Operation of the Noncanonical BK Channel VSD; 2.3. Modulation of BK Voltage-Dependent Gating; 3. Ligand-Dependent Gating in BK Channels; 3.1. Ca2+-Dependent Gating; 3.2. Mg2+-Dependent Gating; 4. The BK Allosteric Gating Mechanism.
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|a 4.1. The HCA and HA Models of Allosteric BK Channel Activation4.2. Electromechanical Coupling; 4.3. Modulation of Electromechanical Coupling; 4.4. Coupling Between the Ca2+ Sensors and the Gate; 4.5. Modulation of BK Ca2+ Sensitivity; 4.6. Coupling Between Voltage and Ca2+ Sensors; 4.7. Coupling Between RCK1 and RCK2 Ca2+ Sensors; 5. The Extraordinary Conductance of BK Channels; 6. Concluding Remarks: The BK Channel as a Rebel and a Model; Acknowledgments; References; Chapter Two: Modulation of BK Channel Function by Auxiliary Beta and Gamma Subunits; 1. Introduction; 2. Discovery.
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|a Big on Bk: Current Insights into the Function of Large Conductance Voltage- and Ca2+- Activated K+ Channels at the Molecular, Cellular and Systemic Levels, a volume in the International Review of Neurobiology series, is a comprehensive overview of the state-of-the-art research into this area. It reviews current knowledge and understanding, and also provides a starting point for researchers and practitioners entering the field.
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650 |
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|a Ion channels.
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650 |
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|a SCIENCE
|x Life Sciences
|x Anatomy & Physiology.
|2 bisacsh
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650 |
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|a Ion channels.
|2 fast
|0 (OCoLC)fst00978573
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655 |
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|a Electronic books.
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700 |
1 |
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|a Contet, Candice,
|d 1979-
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776 |
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|i Print version:
|a Contet, Candice.
|t Big on Bk: Current Insights into the Function of Large Conductance Voltage- and Ca2+- Activated K+ Channels at the Molecular, Cellular and Systemic Levels.
|d : Elsevier Science, ©2016
|z 9780128036198
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830 |
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|a International review of neurobiology ;
|v v. 128.
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856 |
4 |
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|u https://www.sciencedirect.com/science/bookseries/00747742/128
|z Full Text via HEAL-Link
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