Advances in virus research. Volume 97 /

• Άλλοι συγγραφείς: Kielian, Margaret, Mettenleiter, Thomas C., Roossinck, Marilyn J.
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Cambridge, MA : Academic Press, 2017.
• Θέματα: Virology.; Viruses.; Electronic books.

Advances in Virus Research, the latest in the series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the current field of virology. The series is a valuable resource for information on all topics of virus research, from bacteriophages to human vi...

Πίνακας περιεχομένων:

• Front Cover; Advances in Virus Research; Copyright; Contents; Contributors; Chapter One: Biomedical and Catalytic Opportunities of Virus-Like Particles in Nanotechnology; 1. What Is a Virus-Like Particle?; 2. The Essentials of Protein VLP Structure; 3. VLPs as Materials; 3.1. Controlling the Self-Assembly Process; 3.2. De Novo VLPs; 3.3. Higher-Order VLP Assemblies; 4. VLPs as Templates for Constrained Material Synthesis; 4.1. Mineralization; 4.2. Constrained Polymerization; 5. VLPs for Biomedical Delivery and Imaging; 5.1. Masking of VLPs; 6. VLPs as Metabolic Compartments.
• 6.1. Why Encapsulate?6.2. Methods of Enzyme/Protein Encapsulation; 6.3. Effects of Single-Enzyme Encapsulation; 6.4. Multienzyme Systems; 7. VLPs as Stimulants of Immunity; 7.1. Pulmonary Reactions to VLPs; 7.2. Routes of Administration; 7.3. Delivery of Whole Antigens in VLPs; 7.4. External Display of Protein Cargo; 7.5. Why Present?; 8. Outlook; Acknowledgments; References; Chapter Two: A Renaissance in Nepovirus Research Provides New Insights Into Their Molecular Interface With Hosts and Vectors; 1. Introduction; 2. Taxonomy and Genome Structure.
• 3. Population Structure, Genetic Diversity, and Evolution4. Genome Expression by Cap-Independent Translation and Polyprotein Processing; 4.1. Cap-Independent Translation; 4.2. Regulated Polyprotein Processing; 5. Replication Proteins and Assembly of Replication Complexes; 6. Virion Structure and Encapsidation; 7. Viral and Plant Factors Implicated in Cell-to-Cell Movement; 8. Host Defense and Virus Counter-Defense Responses; 8.1. RNA Silencing and the Induction of Symptom Recovery in Nepovirus-Infected Plants.
• 8.2. Other Plant Defense Responses: Resistance Genes, Hypersensitive-Like Responses, and SA-Dependent Mechanisms9. Viral Symptom Determinants; 10. Transmission; 11. Disease Management; 12. Conclusions and Future Prospects; Acknowledgments; References; Chapter Three: Have NEC Coat, Will Travel: Structural Basis of Membrane Budding During Nuclear Egress in Herpesviruses; 1. Introduction; 2. The Role of NEC in Membrane Budding; 2.1. The NEC Is Composed of UL31 and UL34; 2.2. The NEC Is Necessary for Nuclear Capsid Budding and Sufficient for INM Vesiculation.
• 2.3. The NEC Is a Complete Membrane-Budding Machine3. NEC Structures; 3.1. The Overall Architecture of the NEC; 3.2. UL31 and UL34 Structures; 3.3. Comparison of the NEC Structures; 3.4. The Complex Interactions at the NEC Interface; 4. The Hexagonal Lattice of the NEC: Structure and Function; 4.1. The NEC Assembles into a Hexagonal Lattice In Vitro; 4.2. Hexagonal Lattice in NEC Crystals Resembles NEC Coats; 4.3. Analysis of NEC/NEC Interactions Within the Crystal Lattices; 4.4. The NEC Assembles into a Hexagonal Lattice at the INM; 4.5. NEC Oligomerization Is Required for Budding.