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04867nam a2200517 4500 |
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ocn973396928 |
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OCoLC |
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20180501122035.0 |
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m o d |
| 007 |
cr cnu|||unuuu |
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170222s2017 maua o 000 0 eng d |
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|a N$T
|b eng
|e rda
|e pn
|c N$T
|d OPELS
|d IDEBK
|d EBLCP
|d N$T
|d YDX
|d OCLCF
|d OCLCQ
|d MEU
|d OCLCA
|d GrThAP
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|a 973518464
|a 973753051
|a 973798849
|a 973909706
|a 974031142
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|a 9780128122648
|q (electronic bk.)
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|a 0128122641
|q (electronic bk.)
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| 020 |
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|a 9780128122631
|q (print)
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|a 0128122633
|q (print)
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| 035 |
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|a (OCoLC)973396928
|z (OCoLC)973518464
|z (OCoLC)973753051
|z (OCoLC)973798849
|z (OCoLC)973909706
|z (OCoLC)974031142
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| 050 |
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4 |
|a QP801.V5
|b F43 v.104eb
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| 072 |
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7 |
|a MED
|x 075000
|2 bisacsh
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| 072 |
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7 |
|a SCI
|x 036000
|2 bisacsh
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| 082 |
0 |
4 |
|a 612.8/1
|2 23
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| 049 |
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|a TEFA
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| 245 |
0 |
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|a Neurotrophins /
|c edited by Gerald Litwack.
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| 264 |
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1 |
|a Cambridge, MA :
|b Academic Press is an imprint of Elsevier,
|c 2017.
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| 300 |
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|a 1 online resource (xviii, 531 pages :
|b illustrations).
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Vitamins and hormones ;
|v volume 104
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| 546 |
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|a Text in English.
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0 |
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|a Online resource; title from PDF title page (ScienceDirect, viewed February 24, 2017).
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0 |
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|a Front Cover; Neurotrophins; Copyright; Contents; Contributors; Preface; Chapter One: Crystal Structures of Neurotrophin Receptors Kinase Domain; 1. Introduction; 1.1. Trk Receptors Global Structure; 2. Crystal Structure of TrkA, TrkB, and TrkC Kinase Domain; 2.1. Trk Kinase Domain apo Structures; 2.2. Trk Kinase Domain Complexed Structures; 3. Pharmacological Approach: The Selectivity Issue; 4. Conclusion and Future Directions; Acknowledgments; References; Chapter Two: BDNF Propeptide: A Novel Modulator of Synaptic Plasticity; 1. Neurotrophins and Their Biological Actions
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| 505 |
8 |
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|a 2. NT Receptors and Their Signaling3. Synthesis, Intracellular Trafficking, and Secretion of BDNF Protein; 4. Modulation of Synaptic Function by BDNF; 5. BDNF Prodomain: New Roles Beyond a Molecular Chaperone; 6. BDNF and Its Propeptide Are Localized in Presynaptic Dense Core Vesicles; 7. The BDNF Propeptide Is a Novel Synaptic Modulator; 8. Role of the Val66Met Polymorphism in BDNF Propeptide-Dependent LTD; 9. Discussion; References; Chapter Three: Zinc Interactions With Brain-Derived Neurotrophic Factor and Related Peptide Fragments; 1. Introduction; 2. Brain-Derived Neurotrophic Factor
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| 505 |
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|a 2.1. Peptides-Mimicking BDNF3. Zinc in the Brain; 3.1. Zinc Metallostasis in the Brain; 4. Zinc(II) Interaction With BDNF and Related Peptides; 4.1. Peptide Delivery; 5. Zinc, BDNF, and Diet; 6. Conclusion; Acknowledgments; References; Chapter Four: Structural Characterization of the p75 Neurotrophin Receptor: A Stranger in the TNFR Superfamily; 1. TNFR Superfamily; 1.1. The p75 Neurotrophin Receptor; 2. Structural Characterization of p75NTR; 2.1. The Extracellular Domain (ECD); 2.1.1. p75ECD Interaction With Neurotrophins; 2.1.2. p75ECD Interaction With Pro-NGF
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8 |
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|a 2.1.3. p75ECD Interaction With Sortilin3. The Transmembrane Domain (TMD); 4. The Intracellular Domain (ICD); 4.1. p75NTR Juxtamembrane Domain (JTM); 4.2. The p75NTR Death Domain (DD); 4.2.1. p75DD-p75DD Symmetric Complex; 4.2.2. p75-DD/p45-DD Interaction; 4.2.3. p75DD-RhoGDI Complex; 4.2.4. p75-DD/RIP2-CARD Complex; 5. Conclusions and Future Directions; Acknowledgments; References; Chapter Five: Releasing Mechanism of Neurotrophic Factors via Polysialic Acid; 1. Introduction; 2. Biochemical Features of BDNF; 3. Regions and Cellular Distribution of BDNF; 4. Extracellular Secretion of BDNF
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| 505 |
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|a 4.1. BDNF Release via Exocytosis4.2. BDNF Release via Polysialic Acid; 5. Conclusion; Acknowledgments; References; Chapter Six: Emergent Role of Coronin-1a in Neuronal Signaling; 1. Introduction; 2. The Coronin Family of Proteins; 2.1. Type I Coronin Family; 2.2. Type II Coronins; 2.3. Type III Coronin; 3. Type I Coronins as Actin Regulators; 4. Coronin-1a as a Signaling Effector Protein; 4.1. Coronin-1a in Pathogen-Host Signaling; 4.2. Coronin-1a as a Regulator of Internalization Mechanisms; 4.3. Coronin-1a Is Required for GPCR Activation in Excitatory Neurons
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| 650 |
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0 |
|a Nerve growth factor.
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| 650 |
|
7 |
|a MEDICAL / Physiology
|2 bisacsh
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| 650 |
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7 |
|a SCIENCE / Life Sciences / Human Anatomy & Physiology
|2 bisacsh
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| 650 |
|
7 |
|a Nerve growth factor.
|2 fast
|0 (OCoLC)fst01036049
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| 655 |
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4 |
|a Electronic books.
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| 700 |
1 |
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|a Litwack, Gerald,
|e editor.
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| 776 |
0 |
8 |
|c Original
|z 0128122633
|z 9780128122631
|w (OCoLC)961003480
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| 830 |
|
0 |
|a Vitamins and hormones ;
|v v. 104.
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| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/00836729/104
|z Full Text via HEAL-Link
|
