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04967nam a2200505 4500 |
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ocn987790920 |
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OCoLC |
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20180501122036.0 |
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m o d |
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cr cnu|||unuuu |
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170523s2017 mau o 000 0 eng d |
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|a N$T
|b eng
|e rda
|e pn
|c N$T
|d OPELS
|d YDX
|d IDEBK
|d EBLCP
|d N$T
|d OCLCF
|d OCLCQ
|d OTZ
|d CUS
|d OCLCO
|d D6H
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|c (S
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|a 987848864
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|a 9780128021965
|q (electronic bk.)
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|a 0128021969
|q (electronic bk.)
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|a 9780128021729
|q (print)
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|a 0128021721
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|a (OCoLC)987790920
|z (OCoLC)987848864
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|a QH603.C43
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| 072 |
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7 |
|a SCI
|x 007000
|2 bisacsh
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0 |
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|a 572.8/845
|2 23
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| 049 |
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|a TEFA
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| 245 |
0 |
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|a Nuclear receptors in development and disease /
|c edited by Douglas Forrest and Sophia Tsai.
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| 264 |
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1 |
|a Cambridge, MA :
|b Academic Press is an imprint of Elsevier,
|c 2017.
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Current topics in developmental biology ;
|v volume 125
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|a Online resource; title from PDF title page (ScienceDirect, viewed May 24, 2017).
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8 |
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|a AcknowledgmentsReferences; Chapter Three: Nuclear Receptors in Skeletal Homeostasis; 1. Introduction; 1.1. Bone and Bone Cells; 1.2. Nuclear Receptors; 2. NRs and Bone Homeostasis; 2.1. Estrogen Receptor; 2.1.1. Estrogens and Bone Health; 2.1.2. ER Knockout Models; 2.1.3. Mechanisms; 2.2. Androgen Receptor; 2.3. Glucocorticoid Receptor; 2.4. Peroxisome Proliferator-Activated Receptor; 2.4.1. Peroxisome Proliferator-Activated Receptor [alpha]; 2.4.2. Peroxisome Proliferator-Activated Receptor [delta]/[beta]; 2.4.3. Peroxisome Proliferator-Activated Receptor [gamma]; 2.5. Vitamin D Receptor
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| 505 |
8 |
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|a 2.6. Retinoid Acid Receptor and RXR2.7. Estrogen Receptor-Related Receptor; 2.8. NR4A Orphan NRs; 3. Conclusions; Acknowledgments; References; Chapter Four: Estrogen Hormone Biology; 1. Introduction; 2. Cell Mechanisms; 3. Uterine Estrogen Response; 3.1. Genetic Control of Estrogen Responses; 3.2. ER[alpha] Mutations Demonstrate Uterine Mechanisms; 3.3. Tethered Pathway Analysis Using DNA-Binding Deficient ER[alpha] Mutants; 3.4. Analysis of AF-1- and AF-2-Mediated Responses; 3.5. Analysis of Biological Impact of Membrane-Initiated Signaling; 3.6. ER[beta] Does Not Impact Uterine Responses
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|a 3.7. Importance of ER[alpha] to Uterine Function Informs Mechanisms of Disease4. ER in the Ovary; 4.1. Ovarian Phenotypes of ER[alpha] Mutant Mice; 4.2. Ovary-Specific ER[alpha] Knockouts; 4.3. Ovarian Phenotypes of ER[beta] Mutant Mice; 4.4. Role of ER[beta] Signaling in Granulosa Cells; 4.5. Ovarian Phenotypes of ER[alpha] and ER[beta] Compound Mutant Mice; 4.6. Ovarian Phenotypes in Mice Lacking Estradiol Synthesis; 5. ER in Metabolism; 5.1. Metabolic Phenotype of ER[alpha] Knockout Mice; 5.2. Physiological Role of ER[alpha] Transactivation Domains in Metabolism; 5.3. Phenotype of ER[alpha] DNA-Binding Domain Mutant Mice in Metabolism
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| 505 |
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|a Front cover; Nuclear Receptors in Development and Disease; Copyright; Contents; Contributors; Preface; Chapter One: Evolution of Nuclear Receptors and Ligand Signaling: Toward a Soft Key-Lock Model?; 1. Introduction; 2. The Ligand-Receptor Couple for NRs; 3. NR Diversification During Animal Evolution; 4. Evolution of Ligand Binding; 5. Alternative Ligands; 6. Generalization; References; Chapter Two: The Function and Evolution of Nuclear Receptors in Insect Embryonic Development; 1. Introduction: Nuclear Receptor Structure and Function; 2. Roles of NRs in Drosophila Embryonic Development
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| 505 |
8 |
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|a 2.1. Nuclear Receptors and Early Patterning Mechanisms2.2. Functions of NRs During Neurogenesis; 2.3. A Cascade of NR Activity in Response to Ecdysone Mediates Mid-Embryogenesis Morphogenetic Movements and Recalibrates ...; 2.4. Functions of NRs in Morphogenesis and Maturation of Metabolic Organs; 2.5. Other NR Functions During Organogenesis; 2.6. Future Directions; 3. Functional Analysis of NRs in Nonmodel Insects; 3.1. Insects Are the Most Diverse Group on the Planet; 3.2. Genomic Inventory of NRs Across Insect Species; 3.3. Functional Studies of NRs in Emerging Insect Model Systems
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| 650 |
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0 |
|a Nuclear receptors (Biochemistry)
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| 650 |
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7 |
|a SCIENCE / Life Sciences / Biochemistry
|2 bisacsh
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| 650 |
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7 |
|a Nuclear receptors (Biochemistry)
|2 fast
|0 (OCoLC)fst01040875
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| 655 |
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4 |
|a Electronic books.
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| 700 |
1 |
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|a Forrest, Douglas
|c (Molecular biologist),
|e editor.
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| 700 |
1 |
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|a Tsai, Sophia,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Nuclear receptors in development and disease.
|d Cambridge, MA : Elsevier Academic Press, 2017
|z 9780128021729
|w (OCoLC)965344275
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| 830 |
|
0 |
|a Current topics in developmental biology ;
|v v. 125.
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| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/00702153/125
|z Full Text via HEAL-Link
|
