Correlative light and electron microscopy III /

• Other Authors: Müller-Reichert, Thomas, 1962- (Editor), Verkade, Paul (Editor)
• Format: eBook
• Language: English
• Published: Amsterdam, Netherlands ; Boston, Mass. : Elsevier / Academic Press, [2017]
• Series: Methods in cell biology ; v. 140.
• Subjects: Electron microscopy > Technique.; SCIENCE > Electron Microscopes & Microscopy.; SCIENCE / General; Microscopy, Electron > methods.; Light.; Electronic books.
• Physical Description: 1 online resource (xvii, 352 pages) : illustrations (some color).
• Bibliography: Includes bibliographical references.
• ISBN: 9780128099759; 9780128099766; 0128099763; 0128099755
• ISSN: 0091-679X ;

The combination of electron microscopy with transmitted light microscopy (termed correlative light and electron microscopy; CLEM has been employed for decades to generate molecular identification that can be visualized by a dark, electron-dense precipitate. This new volume of Methods in Cell Biology covers many areas of CLEM including a brief history and overview on CLEM methods, imaging of intermediate stages of meiotic spindle assembly in C. elegans embryos using CLEM, and capturing endocytic segregation events with HPF-CLEM. Covers many areas of CLEM by the best international scientists in the field. Includes a brief history and overview on CLEM methods.