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20180501122037.0 |
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170823s2017 mau ob 000 0 eng d |
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|a IDEBK
|b eng
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|c IDEBK
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|d OPELS
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|a 1001740854
|a 1001919155
|a 1004759975
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|a 9780128122808
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|a (OCoLC)1003888802
|z (OCoLC)1001740854
|z (OCoLC)1001919155
|z (OCoLC)1004759975
|z (OCoLC)1005260150
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|a SCI
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|a 572.8
|2 23
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|a TEFA
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|a Advances in genetics.
|n Volume 98 /
|c editors, Theodore Friedmann, Jay C. Dunlap, Stephen F. Goodwin.
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| 250 |
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|a First edition.
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| 264 |
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1 |
|a Cambridge, MA :
|b Academic Press,
|c 2017.
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| 300 |
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|a 1 online resource.
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| 336 |
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|a text
|b txt
|2 rdacontent
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|a computer
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|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Online resource; title from PDF title page (EBSCO, viewed October 12, 2017).
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| 504 |
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|a Includes bibliographical references.
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| 520 |
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|a "Advances in Genetics, Volume 98 provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions. Topics of interest in this updated volume include the Genetics of Mitochondrial Disease, a Genetic analysis of depression, happiness and other normal personality traits, The Evolving Centromere and Kinetochore, and The Genetics of Parkinson's Disease. Critically analyzes future directions for the study of clinical genetics. Written and edited by recognized leaders in the field. Presents new medical breakthroughs that are occurring as a result of advances in our knowledge of genetics"--
|c Provided by publisher.
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|a Front Cover; Advances in Genetics; ADVANCES IN GENETICS, VOLUME 98; ADVANCES IN GENETICS; Contents; CONTRIBUTORS; One -- Evolving Centromeres and Kinetochores; 1. INTRODUCTION; 2. CENTROMERES: FROM POINT TO HOLO; 2.1 Fungal Centromeres; 2.1.1 All the Centromere Diversity in One Kingdom; 2.2 Plant Centromeres; 2.2.1 Long and Retro; 2.3 Animal Centromeres; 2.4 Holocentrics; 2.5 Centromere Summary; 3. KINETOCHORE PROTEINS: SIMILAR YET SO DIVERSE; 3.1 CENP-A; 3.1.1 Building the Foundation for the Kinetochore; 3.2 Inner Kinetochore; 3.2.1 The Protein Web of Chromosome Segregation
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|a 3.3 The Outer Kinetochore3.3.1 The Flexible, Load-Bearing Bridge-to-Spindle Microtubules; 4. FUNGAL OPPORTUNITIES; 5. SUMMARY AND OUTLOOK; ACKNOWLEDGMENTS; REFERENCES; FURTHER READING; Two -- The Genetics of Parkinson Disease; 1. TIMELINE OF PARKINSON DISEASE RESEARCH; 2. ENVIRONMENTAL BASIS OF PARKINSON DISEASE; 3. GENETIC BASIS OF PARKINSON DISEASE; 4. AUTOSOMAL DOMINANT PARKINSON DISEASE; 4.1 Pathogenic Role of SNCA; 4.2 Pathogenic Role of LRRK2; 5. AUTOSOMAL RECESSIVE PARKINSON DISEASE; 5.1 PRKN; 5.2 PINK; 5.3 DJ-1; 6. THE PAST AND THE FUTURE OF PARKINSON DISEASE THERAPIES; 7. CONCLUSIONS
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|a 5.1.2 Kearns-Sayre Syndrome5.1.3 Chronic Progressive External Ophthalmoplegia; 5.2 Mitochondrial DNA-Encoded Maternally Inherited Diseases; 5.2.1 Leigh Syndrome; 5.2.2 Neuropathy, Ataxia, and Retinitis Pigmentosa; 5.2.3 Leber Hereditary Optic Neuropathy; 5.2.4 Myoclonus, Epilepsy With Ragged Red Fibers; 5.2.5 Mitochondrial Encephalomyopathy, Lactic Acidosis, and Strokelike Episodes; 6. NUCLEAR-ENCODED MITOCHONDRIAL DISORDERS; 6.1 Disorders of Mitochondrial DNA Integrity and Stability; 6.1.1 Mitochondrial DNA Replication Apparatus; 6.1.2 Defects in Deoxyribonucleoside Triphosphates Pool
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| 505 |
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|a 6.1.3 Mitochondrial Network Dynamics6.1.4 Mitochondrial Transcription; 6.1.5 Mitochondrial Protein Synthesis and Maintenance; 6.1.6 Mitochondrial Protein Impart; 6.1.7 Mitochondrial Carrier Transporters; 6.1.8 Unclear Function; 6.2 Defects in mtRNA Translation; 6.2.1 Mitoribosome Assembly; 6.2.2 mt-tRNA Aminoacylation; 6.2.3 mt-tRNA Processing and Modification; 6.2.4 mt-mRNA Processing; 6.2.5 Mitochondrial Translation; 6.3 Defects of the Inner Mitochondrial Membrane Lipid Environment; 6.4 Nuclear-Encoded Mitochondrial Electron Transport Chain Subunits and Assembly/Ancillary Factors
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| 650 |
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0 |
|a Genetics.
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| 650 |
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7 |
|a SCIENCE / Life Sciences / Biochemistry.
|2 bisacsh
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| 650 |
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7 |
|a Genetics.
|2 fast
|0 (OCoLC)fst00940117
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| 655 |
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4 |
|a Electronic books.
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| 655 |
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|a Electronic books.
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| 700 |
1 |
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|a Friedmann, Theodore,
|d 1935-
|e editor.
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| 700 |
1 |
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|a Dunlap, Jay C.,
|e editor.
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| 700 |
1 |
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|a Goodwin, Stephen F.,
|e editor.
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| 856 |
4 |
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|u https://www.sciencedirect.com/science/bookseries/00652660/98
|z Full Text via HEAL-Link
|
