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05247nam a2200661 4500 |
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on1007224849 |
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OCoLC |
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20180501122038.0 |
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171020s2017 mauad ob 000 0 eng d |
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|a IDEBK
|b eng
|c IDEBK
|d N$T
|d EBLCP
|d YDX
|d OPELS
|d OHS
|d OCLCO
|e rda
|d MEU
|d GrThAP
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|a 1007310184
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|a 0128120177
|q (electronic bk.)
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|a 9780128120170
|q (electronic bk.)
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|a 9780128120163
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|a 0128120169
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|a (OCoLC)1007224849
|z (OCoLC)1007310184
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4 |
|a RC270.8
|b .S454 2017eb
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| 072 |
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|a HEA
|x 039000
|2 bisacsh
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| 072 |
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|a MED
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|2 bisacsh
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|a MED
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|a 616.99406
|2 23
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| 049 |
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|a TEFA
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|a Selenium and Selenoproteins in Cancer /
|c edited by Kenneth D. Tew, Francesco Galli.
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| 250 |
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|a First edition.
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| 264 |
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1 |
|a Cambridge, MA :
|b Academic Press,
|c 2017.
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| 300 |
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|a 1 online resource (xiv, 302 pages) :
|b illustrations (some color), charts.
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| 336 |
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|a text
|b txt
|2 rdacontent
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| 337 |
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Advances in cancer research ;
|v v. 136
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| 546 |
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|a Text in English.
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| 504 |
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|a Includes bibliographical references.
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| 505 |
0 |
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|a ""Front Cover""; ""Selenium and Selenoproteins in Cancer""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface""; ""Chapter One: The Epidemiology of Selenium and Human Cancer""; ""1. Introduction""; ""2. Selenium and Cancer: Scope of Research""; ""3. Observational Studies""; ""4. Randomized Controlled Trials""; ""5. The Nutritional Prevention of Cancer Trial""; ""6. The Selenium and Vitamin E Cancer Prevention Trial""; ""7. The Other Trials""; ""8. A Natural Experiment on Selenium and Cancer""; ""9. Selenium in Cancer Therapy""; ""10. Conclusion""; ""Acknowledgments""; ""References""
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| 505 |
8 |
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|a ""Chapter Two: Selenoproteins in Tumorigenesis and Cancer Progression""""1. Introduction""; ""2. Selenoprotein Production""; ""3. Investigating Selenoproteins Through Sec tRNA Mutations""; ""4. Role of Specific Selenoproteins in Tumorigenesis""; ""4.1. Selenoprotein P""; ""4.2. Glutathione Peroxidases""; ""4.3. Thioredoxin Reductases""; ""4.4. Selenoprotein F""; ""5. Considerations and Conclusions""; ""Acknowledgments""; ""References""; ""Chapter Three: Selenoproteins and Metastasis""; ""1. Introduction""; ""2. Metastasis""; ""2.1. Local Invasion""; ""2.2. Intravasation""
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|a ""2.3. Survival in Vasculature, Extravasation, and Formation of Micrometastases""""3. Dietary Selenium and Selenium Supplementation""; ""4. Thioredoxin Reductases and Redox Tone""; ""5. GPX and ROS Regulation""; ""6. Selenoproteins Involved in ER Stress and Calcium Flux""; ""7. Other Potential Roles for Selenoproteins in Metastasis""; ""8. Conclusions""; ""Acknowledgments""; ""References""; ""Chapter Four: Selenium-Dependent Glutathione Peroxidases During Tumor Development""; ""1. Introduction""; ""2. Expression Profile of Se-Dependent GPxes in Different Types of Tumors""
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|a ""3. Hydroperoxides and Redox Signaling During Cancer Development""""4. Impact of Individual GPxes on Tumor Development""; ""4.1. GPx1""; ""4.1.1. Cell Death""; ""4.1.2. Redox Signaling""; ""4.1.3. Metabolism""; ""4.2. GPx2""; ""4.2.1. Cell Death""; ""4.2.2. Redox Signaling""; ""4.3. GPx3""; ""4.3.1. Cell Death""; ""4.3.2. Redox Signaling""; ""4.4. GPx4""; ""4.4.1. Cell Death""; ""4.4.2. Redox Signaling""; ""5. Conclusions""; ""Acknowledgment""; ""References""; ""Chapter Five: Targeting the Selenoprotein Thioredoxin Reductase 1 for Anticancer Therapy""; ""1. Introduction""
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|a ""1.1. The Thioredoxin System""""1.2. Thioredoxin Reductase 1""; ""2. TrxR1 as an Important Enzyme in Cancer""; ""3. Conclusions""; ""Acknowledgments""; ""References""; ""Chapter Six: The Regulation of Pathways of Inflammation and Resolution in Immune Cells and Cancer Stem Cells by Selenium""; ""1. Tumor Microenvironment: Interplay With Immune Cells and Pathways of Inflammation""; ""2. Selenium-Dependent Effects on Cancer Stem Cells in Leukemia""; ""3. Interaction of LSCs With Immune Cells Mediated by CyPGs""; ""4. Targeting LSC Metabolism With Selenium""; ""5. Summary""; ""Acknowledgments""
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| 650 |
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0 |
|a Cancer
|x Treatment.
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| 650 |
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0 |
|a Selenium
|x Physiological effect.
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| 650 |
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0 |
|a Selenoproteins
|x Physiological effect.
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| 650 |
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2 |
|a Neoplasms.
|0 (DNLM)D009369
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| 650 |
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2 |
|a Selenium.
|0 (DNLM)D012643
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| 650 |
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2 |
|a Selenoproteins.
|0 (DNLM)D051140
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| 650 |
|
7 |
|a HEALTH & FITNESS / Diseases / General.
|2 bisacsh
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| 650 |
|
7 |
|a MEDICAL / Clinical Medicine.
|2 bisacsh
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| 650 |
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7 |
|a MEDICAL / Diseases.
|2 bisacsh
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| 650 |
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7 |
|a MEDICAL / Evidence-Based Medicine.
|2 bisacsh
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| 650 |
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7 |
|a MEDICAL / Internal Medicine.
|2 bisacsh
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| 655 |
|
4 |
|a Electronic books.
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| 700 |
1 |
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|a Tew, Kenneth D.,
|e editor.
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| 700 |
1 |
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|a Galli, Francesco,
|e editor.
|
| 776 |
0 |
8 |
|c Original
|z 9780128120163
|z 0128120169
|w (OCoLC)982089162
|
| 830 |
|
0 |
|a Advances in cancer research ;
|v v. 136.
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| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/0065230X/136
|z Full Text via HEAL-Link
|
