Nanomedicine in Central Nervous System Injury and Repair /
Nanomedicine in Central Nervous System Injury and Repair (IRN), Volume 137, the latest release in the International Review of Neurobiology series presents comprehensive chapters that cover a broad range of topics, including, but not limited to, how Diabetes exacerbates methamphetamine induced blood-...
| Άλλοι συγγραφείς: | , |
|---|---|
| Μορφή: | Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Cambridge, MA :
Academic Press,
2017.
|
| Σειρά: | International review of neurobiology ;
v. 137. |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- ""Front Cover""; ""Nanomedicine in Central Nervous System Injury and Repair""; ""Copyright""; ""Contents""; ""Contributors""; ""Preface""; ""References""; ""Acknowledgments""; ""Chapter One: Current Strategies for the Delivery of Therapeutic Proteins and Enzymes to Treat Brain Disorders""; ""1. Introduction""; ""2. Physical Delivery""; ""3. Nonphysical Methods""; ""3.1. Systemic Delivery""; ""3.2. In Vitro Targeting""; ""3.3. In Vivo Proteins, Fusion Proteins, and Modified Enzymes""; ""3.4. Nanoparticle-Based Delivery""; ""4. Conclusion""; ""References""
- ""Chapter Two: Impact of Inflammation on the Blood-Neural Barrier and Blood-Nerve Interface: From Review to Therapeutic Preview""""1. Introduction""; ""2. Blood-Nerve Interface""; ""3. Mast Cells and the BBB""; ""4. Immune Cell Interactions Amplify Neuroinflammation""; ""5. Neuroinflammation and Aging""; ""6. Mast Cells and Glia as Therapeutic Targets""; ""7. Conclusion and Perspectives""; ""Acknowledgments""; ""Conflict of Interest""; ""References""; ""Chapter Three: Intravenous Administration of Functionalized Magnetic Iron Oxide Nanoparticles Does Not Induce CNS Injury ...""
- ""1. Introduction""""1.1. Magnetic Iron Oxide Nanoparticles""; ""1.2. Polymer-Coated Iron Oxide Nanoparticles""; ""1.3. Superparamagnetic Iron Oxide Nanoparticles""; ""2. Experimental Procedures""; ""3. SCI Model""; ""4. Nanoparticle Administration""; ""5. Treatment With Cerebrolysin""; ""5.1. Blood-Spinal Cord Barrier/BBB Permeability""; ""5.2. Edema Formation""; ""5.3. Morphological Changes in the Cord""; ""5.4. Experimental Observations""; ""5.4.1. Iron Oxide Nanoparticles Effect on BSCB/BBB Permeability""; ""5.4.2. Morphological Changes Inside the Cord""
- ""6. Effects of Cerebrolysin on BBB/BSCB Permeability""""6.1. Effects of Cerebrolysin on Neuronal and Glial Cell Damage""; ""6.2. Probable Mechanisms of IOMNP-Induced Neurotoxicity""; ""6.3. Cerebrolysin-Induced Neuroprotection""; ""7. Conclusion and Future Perspectives""; ""Acknowledgments""; ""References""; ""Chapter Four: Histaminergic Receptors Modulate Spinal Cord Injury-Induced Neuronal Nitric Oxide Synthase Upregulation and ...""; ""1. Introduction""; ""2. Histamine in the Spinal Cord""; ""3. Histamine and Nitric Oxide Interaction""
- ""4. Histamine and the Spinal Cord Microcirculation""""5. Histamine and the BSCB Permeability""; ""6. Histamine and Spinal Cord Edema""; ""7. Nanowired Drug Delivery Enhances Neuroprotection""; ""8. Our Investigations on Histamine-Receptor Modulation and nNOS Expression in SCI""; ""8.1. Animals""; ""8.2. Spinal Cord Injury""; ""8.3. Drug Treatments""; ""8.4. TiO2-Nanowired Delivery of Cimetidine and Ranitidine""; ""8.5. Parameters Measured""; ""8.6. BSCB Permeability""; ""8.7. Spinal Cord Edema""; ""8.8. Spinal Cord Blood Flow""; ""8.9. Morphological Analyses""
