Advances in Biomembranes and Lipid Self-Assembly. Volume 27 /

• Άλλοι συγγραφείς: Iglič, Aleš (Επιμελητής έκδοσης), Rappolt, Michael (Επιμελητής έκδοσης), Garcia-Saez, Ana (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: San Diego : Elsevier Science, 2018.
• Σειρά: Advances in Biomembranes and Lipid Self-Assembly ; Volume 27
• Θέματα: Bilayer lipid membranes > Biotechnology > Periodicals.; Liposomes > Periodicals.; SCIENCE > Chemistry > Industrial & Technical.; TECHNOLOGY & ENGINEERING > Chemical & Biochemical.; Bilayer lipid membranes > Biotechnology.; Liposomes.; Electronic books.; Periodicals.

Πίνακας περιεχομένων:

• Front Cover; Advances in Biomembranes and Lipid Self-Assembly; Copyright; Contents; Contributors; Preface; Chapter One: The Role of Self-Assembling Lipid Molecules in Vaccination; 1. Introduction; 2. Immune Response to Lipids; 2.1. Innate Immune Response to Lipids; 2.2. Lipid-Stimulated PRRs (TLR4); 2.3. TLR4 Signaling; 3. Lipids, Lipid Derivatives, and Lipid Mimetics as Vaccine Adjuvants; 3.1. TLR4-Directed Vaccine Adjuvants Beyond Lipid A; 3.2. Lipid A Derivatives as Vaccine Adjuvants; 3.3. Small Molecule TLR4 Adjuvants; 3.4. Challenges With Animal Models for TLR4 Adjuvant Development.
• 4. Lipid-Based Self-Assembling Vesicle as Vaccine Platforms4.1. Lipid-Based Nanovesicles as Vaccine Platforms; 4.2. Liposomes as Vaccine Platforms; 4.3. Liposome Antigens and Adjuvants; 4.4. VLPs-Based Vaccines; 4.4.1. Icosahedral and Spherical VLPs; 4.4.2. Filamentous VLPs; 4.5. Utilizing VLPs in the Context of a Highly Pathogenic Virus Research; 4.5.1. Entry; 4.5.2. Budding; References; Further Reading; Chapter Two: The Role of Mitochondrial Outer Membrane Permeabilization (MOMP) in Apoptosis: Studying Bax Pores by Cryo-El ... ; 1. Introduction; 2. In Vitro Reconstitution of MOMP (Fig. 1).
• 2.1. Outer Membrane Vesicles2.2. Liposomes; 3. Bax Pores Revealed in Liposomes and OMVs by Cryo-Electron Microscopy; 3.1. Freezing Optimization; 3.2. Bax Pores in Liposomes; 3.3. Bax Pores in OMVs; 4. Bax Localization in the Pore; 4.1. Direct and Indirect Labeling of Bax With Nanogold; 4.1.1. Direct Labeling of Bax; 4.1.2. Indirect Labeling of Bax; 4.2. Bax Localization on the Pore Edges; 4.3. Bax Pores in Apoptotic Mitochondria; 5. Possible Pore Formation Mechanisms; 5.1. Bax/Bak Dimer/Oligomer Formation During MOMP; 5.2. Role for a Single Bax Molecule in Pore Formation?
• 5.3. Membrane Permeabilization Induced by Antimicrobial Peptides6. Summary and Future Directions; Acknowledgments; References; Chapter Three: Electrochemical Biosensor Based on TiO2 Nanomaterials for Cancer Diagnostics; 1. Introduction; 2. Cancer; 2.1. Pathology; 2.2. Cancer Diagnostic: Current Issues; 3. Toward Novel Methods of Cancer Diagnosis; 3.1. Biosensor; 3.1.1. Molecular Recognition Element in Biosensor; 3.1.2. Transducers in Biosensor; 3.2. Electrochemical Biosensor and Electrochemical Detection Techniques; 3.2.1. Voltammetric/Amperometric Biosensors; 3.2.2. Impedimetric Biosensors.
• 3.2.3. Conductometric and Capacitive Biosensors3.2.4. Potentiometric Biosensors; 3.2.5. Field Effect Transistor (FET)-Based Biosensors; 4. Nanosized Materials; 4.1. TiO2 Nanomaterials in Biomedicine; 4.2. Important Characteristics of TiO2 Nanomaterials for Biosensor Applications; 4.2.1. Specific Surface Area; 4.2.2. Wettability; 4.3. Interactions TiO2 Nanomaterials: Biological Material; 4.3.1. Effect of Gaseous Plasma Surface Treatment; 4.3.2. Effect of Electron Transfer Rate; 5. TiO2 Biosensors; 5.1. TiO2 Biosensors for Human Cancer Detection; 6. Conclusions; References; Further Reading.