Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists

• Main Author: Kwon, Younggil (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US, 2002.
• Subjects: Medicine.; Pharmacy.; Pharmacology.; Biochemistry.; Biomedicine.; Pharmacology/Toxicology.; Biochemistry, general.

In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization. During discovery phase...

Table of Contents:

• Pharmacokinetic Study Design and Data Interpretation
• New Approaches for High Throughput In Vivo Exposure Screening
• Absorption
• Distribution
• Clearance
• Protein Binding
• Metabolism
• Biliary Excretion
• Nonlinear Pharmacokinetics
• Pharmacodynamics and Pharmacokinetic/Pharmacodynamic Relationships
• Predicting Pharmacokinetics in Humans
• Animal Physiology.