Voltage-Gated Calcium Channels

oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar­ macological targ...

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Bibliographic Details
Main Author: Zamponi, Gerald W. (Author)
Corporate Author: SpringerLink (Online service)
Format: Electronic eBook
Language:English
Published: Boston, MA : Springer US, 2005.
Series:Molecular Biology Intelligence Unit
Subjects:
Online Access:Full Text via HEAL-Link
Table of Contents:
  • Ca2+ Chemistry, Storage and Transport in Biologic Systems
  • Monitoring Intracellular Ca2+ in Brain Slices with Fluorescent Indicators
  • A Brief History of Calcium Channel Discovery
  • Biochemical Studies of Voltage-Gated Ca2+ Channels
  • Molecular Properties of Voltage-Gated Calcium Channels
  • Role of ? Subunits in Voltage-Gated Calcium Channel Functions
  • Distribution and Targeting Mechanisms of Voltage Activated Ca2+ Channels
  • The Calcium Channel and the Transmitter Release Site
  • Determinants of G Protein Inhibition of Presynaptic Calcium Channels
  • Phosphorylation-Dependent Regulation of Voltage-Gated Ca2+ Channels
  • Ca2+-Dependent Modulation of Voltage-Gated Ca2+ Channels
  • Voltage-Dependent Inactivation of Voltage Gated Calcium Channels
  • Selective Permeability of Voltage-Gated Calcium Channels
  • The Run-Down Phenomenon of Ca2+ Channels
  • Calcium Channels As Therapeutic Targets
  • Calcium Channelopathies
  • The Molecular Basis of Ca2+ Antagonist Drug Action-Recent Developments
  • Calcium Channel Block and Inactivation
  • Block of Voltage-Gated Calcium Channels by Peptide Toxins
  • Calcium Channels in the Heart
  • Post-Genomic Insights into T-Type Calcium Channel Functions in Neurons
  • Voltage-Gated Ca2+ Channels of the Vertebrate Retina
  • Exploring the Function and Pharmacotherapeutic of Potential Voltage-Gated Ca2+ Channels with Gene-Knockout Models.