A Guide to QTL Mapping with R/qtl

• Main Authors: Broman, Karl W. (Author), Sen, Saunak (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York, 2009.
• Series: Statistics for Biology and Health,
• Subjects: Life sciences.; Biochemistry.; Animal genetics.; Statistics.; Life Sciences.; Biochemistry, general.; Statistics for Life Sciences, Medicine, Health Sciences.; Animal Genetics and Genomics.

Quantitative trait locus (QTL) mapping is used to discover the genetic and molecular architecture underlying complex quantitative traits. It has important applications in agricultural, evolutionary, and biomedical research. R/qtl is an extensible, interactive environment for QTL mapping in experimen...

Table of Contents:

• Importing and simulating data
• Data checking
• Single-QTL analysis
• Non-normal phenotypes
• Experimental design and power
• Working with covariates
• Two-dimensional, two-QTL scans
• Fit and exploration of multiple-QTL models
• Case study I
• Case study II.