RHO Family GTPases

• Corporate Author: SpringerLink (Online service)
• Other Authors: Manser, Ed (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2005.
• Series: Proteins and Cell Regulation ; 3
• Subjects: Life sciences.; Cancer research.; Molecular biology.; Biochemistry.; Proteomics.; Enzymology.; Cell biology.; Life Sciences.; Cell Biology.; Biochemistry, general.; Cancer Research.; Molecular Medicine.

Humans contain more than 20 Rho type GTPases. This volume not only presents a detailed phylogenetic analysis of Rho proteins, but also discusses the possible origins of the human members. Such an analysis of human Rho GTPases has not previously been attempted. The book includes an overview of how Rh...

Table of Contents:

• The Rho GTPases
• Evolution of the Human Rho GTPase Family
• Structural Analysis of Rho Protein Complexes
• Activation of GTPases by Dock180 Family of Proteins
• Rho GAPs — Regulators of Rho GTPases and More
• RhoA/C and the Actin Cytoskeleton
• Cdc42 and Rac Control of the Actin Cytoskeleton
• Regulation of Cell-Cell Adhesion by Rho Family GTPases
• Rho Proteins and Vesicle Trafficking
• The Prototype Rho-Associated Kinase PAK
• Genetic Analysis of Rho Protein Function in Mice
• Rho Proteins and Microtubules.