Innate and Adaptive Immunity in the Tumor Microenvironment

• Corporate Author: SpringerLink (Online service)
• Other Authors: Yefenof, Eitan (Editor)
• Format: Electronic eBook
• Language: English
• Published: Dordrecht : Springer Netherlands, 2008.
• Series: The Tumor Microenvironment ; 1
• Subjects: Medicine.; Cancer research.; Immunology.; Oncology.; Cell biology.; Biomedicine.; Cancer Research.; Cell Biology.; Biomedicine general.

Cancer cells are continuously interacting with the immune system of the host. These interactions can be regarded as a double edged sword. On the one hand, innate and adaptive immune responses act to protect the host by attempting rejection of the tumor. On the other hand, inflammatory cells and prot...

Table of Contents:

• Immune Effector Cells in the Tumor Microenvironment: Their Role in Regulation of Tumor Progression
• Histocompatibility Antigens, Tumor Microenvironment and Escape Mechanisms Utilized by Tumor Cells
• Local Tumor Growth and Spontaneous Systemic T Cell Responses in Cancer Patients: A Paradox and Puzzle
• Insights into Mechanisms of Immune Resistance in the Tumor Microenvironment through Molecular Profiling
• Tumor Antigens as Modulators of the Tumor Microenvironment
• Tumor Cell Resistance to Apoptosis by Infi ltrating Cytotoxic Lymphocytes
• The Tumor Microenvironment as a Model for Tissue-Specific Rejection
• Functional Cytotoxicity of T Cells in the Tumor Microenvironment
• Natural Killer Cells at the Tumors Microenvironment
• Contribution of the Microenvironment to the Pathogenesis of EBV-Positive Hodgkin and Nasal NK/T-cell Lymphomas.