Development of Antibody-Based Therapeutics Translational Considerations /
Development of Antibody-Based Therapeutics: Translational Considerations examines important considerations necessary for the design of effective translational strategies during the development of antibody-based therapeutics. Translational strategies for development of antibody-based therapeutics req...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | , , |
| Μορφή: | Ηλεκτρονική πηγή Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
New York, NY :
Springer New York,
2012.
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| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Translational Strategies for Development of Antibody-Based Therapeutics: An Overview
- Discovery Process for Antibody-Based Therapeutics
- Technologies for the Generation of Human Antibodies
- Application of Antibody Engineering in the Development of Next Generation Antibody-Based Therapeutics
- Biophysical Considerations
- Considerations in Establishing Affinity Design Goals
- BioAnalytical Considerations: Pharmacokinetics and Immunogenicity
- Antibody-Based Therapeutics in Oncology : Preclinical Considerations
- Factors Impacting the Tumor Localization and Distribution
- Antibody-Based Therapeutics: Preclinical Safety Considerations
- Application of Pharmacokinetic/Pharmacodynamic Modeling
- Design of Translational Strategies : Application of Population Pharmacokinetic-Pharmacodynamic (PK-PD) Approaches
- Translational Biomarkers: Essential Tools in Development of Antibody-Based Therapeutics
- Development of Antibody-Based Therapeutics: Translational Research in Alzheimer’s Disease
- Considerations in Manufacturing Process Development
- Next Generation Antibody-Based Therapeutics
- Immune Complex Therapies for Treatment of Immune Thrombocytopenia (ITP)
- Application of Bioinformatics Principles for Target Evaluation
- Concluding Remarks.
