Pharmacokinetic-Pharmacodynamic Modeling and Simulation

• Main Author: Bonate, Peter L. (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Boston, MA : Springer US : Imprint: Springer, 2011.
• Edition: 2.
• Subjects: Medicine.; Pharmacology.; Biomedicine.; Pharmacology/Toxicology.

Since its publication in 2006, Pharmacokinetic-Pharmacodynamic Modeling and Simulation has become the leading text on modeling of pharmacokinetic and pharmacodynamic data using nonlinear mixed effects models and has been applauded by students and teachers for its readability and exposition of comple...

Table of Contents:

• The Art of Modeling
• Linear Models and Regression
• Nonlinear Models and Regression
• Variance Models, Weighting, and Transformations
• Case Studies in Linear and Nonlinear Modeling
• Linear Mixed Effects Models
• Nonlinear Mixed Effects Models: Theory
• Nonlinear Mixed Effects Models: Practical Issues
• Nonlinear Mixed Effects Models: Case Studies
• Bayesian Modeling
• Generalized Linear Models and Its Extensions
• Principles of Simulation
• Appendix
• Index.