Genetic Damage in Human Spermatozoa

• Corporate Author: SpringerLink (Online service)
• Other Authors: Baldi, Elisabetta (Editor), Muratori, Monica (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2014.
• Series: Advances in Experimental Medicine and Biology, 791
• Subjects: Medicine.; Human genetics.; Endocrinology.; Reproductive medicine.; Biomedicine.; Human Genetics.; Reproductive Medicine.

There are several types of damage that can be found in the male gamete. Genetic damage in spermatozoa can originate during spermatogenesis, or it can originate during transit in both male and female genital tracts. Damage can also be due to ageing, environmental or iatrogenic conditions, as well as...

Table of Contents:

• Structure of chromatin in spermatozoa
• Genomic changes in spermatozoa of aging male
• Chromosomal aberrations and aneuploidies
• The sperm epigenome: implications for the embryo
• Paternal reprogramming of genome: transgenerational effects
• Alterations in protamination
• Sperm DNA fragmentation and base oxidation
• Iatrogenic Genetic damage
• Sperm selection: effect on sperm DNA quality
• Effect of antioxidant treatments on sperm genetic damage
• Index.