Novel Chemical Tools to Study Ion Channel Biology

• Corporate Author: SpringerLink (Online service)
• Other Authors: Ahern, Christopher (Editor), Pless, Stephan (Editor)
• Format: Electronic eBook
• Language: English
• Published: New York, NY : Springer New York : Imprint: Springer, 2015.
• Edition: 1st ed. 2015.
• Series: Advances in Experimental Medicine and Biology, 869
• Subjects: Medicine.; Cell biology.; Biomedicine.; Biomedicine general.; Cell Biology.

This volume describes chemical approaches to assess ion channel structure, function and pharmacology. Topics discussed include the use of engineered ionizable side chains to obtain information on permeation pathways and the local environment; the modification of engineered cysteine side chains, incl...