Current Applications for Overcoming Resistance to Targeted Therapies

• Corporate Author: SpringerLink (Online service)
• Other Authors: Szewczuk, Myron R. (Editor, http://id.loc.gov/vocabulary/relators/edt), Qorri, Bessi (Editor, http://id.loc.gov/vocabulary/relators/edt), Sambi, Manpreet (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2019.
• Edition: 1st ed. 2019.
• Series: Resistance to Targeted Anti-Cancer Therapeutics, 20
• Subjects: Cancer research.; Molecular biology.; Cancer Research.; Molecular Medicine.

Targeted therapies were initially developed to exploit the upregulation and dependence on key oncogenic pathways critical to cancer progression. Additionally, they also presented as a method to overcome chemoresistance by supplementing conventional therapeutic regimens with targeted therapies. Howev...

Table of Contents:

• Introduction to the Acquisition of Resistance to Targeted Therapy
• Targeting the Tumor Microenvironment to Overcome Resistance to Targeted Therapy
• Current Challenges and Applications of Oncolytic Viruses in Overcoming Resistance to Therapies in Cancer
• Novel Methods to Overcome Acquired Resistance to Immunotherapy
• Therapies to Overcome Multidrug-Resistant Receptors
• Overcoming Resistance to PARP Inhibition
• Novel Methods of Overcoming HER2 Therapy Resistance in Breast Cancer
• Emerging Novel Therapies for Overcoming Resistance to Targeted Therapies
• Targeting Epigenetic Regulators in Cancer to Overcome Resistance to Targeted Therapy
• Nanomedicine and Drug Delivery Systems in Overcoming Resistance to Targeted Therapy
• Index.