Immunosenescence

• Corporate Author: SpringerLink (Online service)
• Other Authors: Thiel, Andreas (Editor)
• Format: Electronic eBook
• Language: English
• Published: Basel : Springer Basel : Imprint: Springer, 2012.
• Series: Birkhäuser Advances in Infectious Diseases
• Subjects: Medicine.; Immunology.; Molecular biology.; Biomedicine.; Biomedicine general.; Molecular Medicine.

As individuals age, their ability to respond to and clear pathogens and to control unwanted immune reactions declines, leading to a greater incidence of certain infectious diseases, autoimmunity and general immune dysfunctions. Most remarkably, the efficacy of vaccines is frequently decreased in eld...

Table of Contents:

• Regulation of Adaptive Immunity in the Elderly
• Does Innate Immunity Get Old?
• Thy(-Im)Munosenescence: The Ageing of the Thymus and Its Impact on the Immune System
• Characteristics of B Cells and B Cell Responses in Aged Individuals
• Mechanisms of Immune Protection to Pneumococcal Infection in the Young and the Elderly
• CMV Subversion of the Immune System in Later Life
• Aging and Autoimmunity
• Vaccination in the Elderly
• Immunosenescence and the 3r’s; Restoration, Replacement and Reprogramming
• Novel Strategies of Improved Vaccines for Elderly: The Example of Influenza.