Toxicity and Autophagy in Neurodegenerative Disorders

Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principa...

Full description

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Fuentes, José M. (Editor)
Format: Electronic eBook
Language:English
Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
Series:Current Topics in Neurotoxicity, 9
Subjects:
Online Access:Full Text via HEAL-Link
Description
Summary:Comprehensive overview of different aspects of autophagy as it relates to neurodegenerative diseases. The pathogenesis of the main neurodegenerative disorders includes either the accumulation of altered or misfolded proteins or exposure to several toxics. Autophagy constitute one of the two principal cellular pathways implicate in the clearance of these material and can serve as a neuroprotective mechanism. Topics include: the role of autophagy in the brain, the role of autophagy in the principal neurodegenerative disorders, and the mechanism by which different molecules cause neurotoxicity and the role autophagy plays.
Physical Description:XV, 268 p. 34 illus., 27 illus. in color. online resource.
ISBN:9783319139395
ISSN:2363-9563 ;