Correlation Force Spectroscopy for Single Molecule Measurements

• Main Author: Radiom, Milad (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2015.
• Series: Springer Theses, Recognizing Outstanding Ph.D. Research,
• Subjects: Chemistry.; Spectroscopy.; Chemical engineering.; Atomic structure.; Molecular structure.; Spectra.; Microscopy.; Spectroscopy/Spectrometry.; Spectroscopy and Microscopy.; Atomic/Molecular Structure and Spectra.; Industrial Chemistry/Chemical Engineering.
• Physical Description: XXVII, 117 p. 48 illus., 31 illus. in color. online resource.
• ISBN: 9783319140483
• ISSN: 2190-5053

This thesis addresses the development of a new force spectroscopy tool, correlation force spectroscopy (CFS) for the measurement of the properties of very small volumes of material (molecular to µm3) at kHz-MHz frequency range. CFS measures the simultaneous thermal fluctuations of two closely-spaced atomic force microscopy (AFM) cantilevers.  CFS then calculates the cross-correlation in the thermal fluctuations that gives the mechanical properties of the matter that spans the gap of the two cantilevers. The book also discusses development of CFS, its advantages over AFM, and its application in single molecule force spectroscopy and micro-rheology.