NF-κB-Related Genetic Diseases

• Main Authors: Courtois, Gilles (Author), Pescatore, Alessandra (Author), Gautheron, Jérémie (Author), Fusco, Francesca (Author), Ursini, Matilde Valeria (Author), Senegas, Anna (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Edition: 1st ed. 2016.
• Series: SpringerBriefs in Biochemistry and Molecular Biology,
• Subjects: Medicine.; Human genetics.; Molecular biology.; Medical biochemistry.; Biomedicine.; Molecular Medicine.; Human Genetics.; Medical Biochemistry.

This book presents the diverse clinical, cellular and molecular manifestations of NF-KB-related genetic diseases. It shows that studying patient-related pathologies affecting the components of the NF-KB signaling pathway offers the opportunity to understand the various functions of NF-KB in humans,...

Table of Contents:

• 1) The NF-kB signaling pathways: players and Functions
• 2) Genetic Diseases Affecting the Canonical Pathway of NF-kB Activation
• 3) Genetic Diseases Affecting hte Non-Camonical Pathway of NF-kB Activation
• 4) Genetic Diseases Affecting Ubiquitination Processes in NF-kB Signaling
• 5)Lessons Learned from Studying NF-kB Related Genetic Diseases.