Sperm Acrosome Biogenesis and Function During Fertilization

• Corporate Author: SpringerLink (Online service)
• Other Authors: Buffone, Mariano G. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Series: Advances in Anatomy, Embryology and Cell Biology, 220
• Subjects: Medicine.; Human physiology.; Molecular biology.; Reproductive medicine.; Urology.; Biomedicine.; Human Physiology.; Molecular Medicine.; Reproductive Medicine.

Over the last decades, acrosomal exocytosis (also called the “acrosome reaction”) has been recognized as playing an essential role in fertilization. Secretion of this granule is an absolute requirement for physiological fertilization. In recent years, the study of mammalian acrosomal exocytosis has...

Table of Contents:

• Preface
• The acrosome reaction: a historical perspective
• The acrosomal matrix
• Role of ion channels in the sperm acrosome reaction
• The molecules of sperm exocytosis
• Sperm capacitation and acrosome reaction in mammalian sperm
• Lipid regulation of acrosome exocytosis
• Role of actin cytoskeleton during mammalian sperm acrosomal exocytosis
• Site of mammalian sperm acrosome reaction.