Interleukin-27: Biological Properties and Clinical Application

• Main Authors: Jankowski, Marek (Author), Wandtke, Tomasz (Author)
• Corporate Author: SpringerLink (Online service)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2016.
• Series: SpringerBriefs in Immunology,
• Subjects: Medicine.; Immunology.; Cytokines.; Growth factors.; Biomedicine.; Cytokines and Growth Factors.

This volume focuses on various aspects of interleukin-27 (IL-27), especially its potential for clinical applications. The authors discuss the downstream signaling from the IL-27 receptor and its molecular targets in immune cells including Th1, Th2, Th17, Treg, Tr1, Tfh, B cells, DCs and macrophages....

Table of Contents:

• IL-27: Structure, Regulation and Variability
• IL-27: A Key Player in Immune Regulation
• IL-27 in Health and Disease.