Bone Morphogenetic Proteins: Systems Biology Regulators

• Corporate Author: SpringerLink (Online service)
• Other Authors: Vukicevic, Slobodan (Editor), Sampath, Kuber T. (Editor)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2017.
• Series: Progress in Inflammation Research
• Subjects: Medicine.; Immunology.; Proteins.; Cytokines.; Growth factors.; Systems biology.; Cell biology.; Biomedicine.; Cell Biology.; Cytokines and Growth Factors.; Protein Science.; Systems Biology.

This book focuses on the salient features of the biology of Bone Morphogenetic Proteins and the advances in our understanding of their structure and function and of downstream signaling, as well as their governance in systems biology from bone and dentin to kidney, cancer, diabetes, iron homeostasis...

Table of Contents:

• Introduction
• BMPs: Historic and Future Perspectives
• BMP – Biology
• BMPs in Development
• BMP signaling
• BMP Antagonists - Biology
• BMP and BMP Antagonists - Structure and Function
• BMPs in Orthopaedic Medicine: Promises and Challenges
• BMP6 and Bone Repair
• BMPs in Dental Medicine: Promises and Challenges
• BMPs in Spine
• BMPs in Articular Joints
• BMP Signaling & FOP
• BMP-7 Biology and its Therapeutic Utility for Chronic Kidney Diseases
• BMPs in Inflammation
• BMPs and Angiogenesis
• BMP Signaling in Iron Homeostasis
• BMP Signaling in Pulmonary Arterial Hypertension
• BMP Signaling and Cancer
• BMP Biology in Rare Diseases.