Nuclear Pore Complexes in Genome Organization, Function and Maintenance

• Corporate Author: SpringerLink (Online service)
• Other Authors: D'Angelo, Maximiliano (Editor, http://id.loc.gov/vocabulary/relators/edt)
• Format: Electronic eBook
• Language: English
• Published: Cham : Springer International Publishing : Imprint: Springer, 2018.
• Edition: 1st ed. 2018.
• Subjects: Medical genetics.; Gene expression.; Cell biology.; Gene Function.; Gene Expression.; Cell Biology.

The three-dimensional organization of the DNA inside the eukaryotic cell nucleus has emerged a critical regulator of genome integrity and function. Increasing evidence indicates that nuclear pore complexes (NPCs), the large protein channels that connect the nucleus to the cytoplasm, play a critical...